Evidence map›Paper›PMID 37755313›Full record

ArticleAdvanced healthcare materials2024

Photothermal Excitation of Neurons Using MXene: Cellular Stress and Phototoxicity Evaluation.

Yingqiao Wang, Jane E Hartung, Adam Goad, Matías A Preisegger, Benjamin Chacon, Michael S Gold, Yury Gogotsi, Tzahi Cohen-Karni

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Astrocyte Interactions With TiAdvanced materials interfaces · 2025
    Article
  4. Review
  5. Simultaneous Detection of Neural Activity and Temperature in Photothermal Neural Stimulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingqiao WangDepartment of Materials Science and Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.ORCID 0000-0002-9294-3705
Jane E HartungDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, PA, 15260, USA.ORCID 0000-0002-5486-9997
Adam GoadA.J. Drexel Nanomaterials Institute and Department of Materials Science and Engineering, Drexel University, Philadelphia, PA, 19104, USA.ORCID 0000-0002-5390-6311
Matías A PreiseggerDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, PA, 15260, USA.ORCID 0009-0001-6939-5552
Benjamin ChaconA.J. Drexel Nanomaterials Institute and Department of Materials Science and Engineering, Drexel University, Philadelphia, PA, 19104, USA.ORCID 0009-0007-3486-9010
Michael S GoldDepartment of Neurobiology, University of Pittsburgh, Pittsburgh, PA, 15260, USA.ORCID 0000-0002-2083-6206
Yury GogotsiA.J. Drexel Nanomaterials Institute and Department of Materials Science and Engineering, Drexel University, Philadelphia, PA, 19104, USA.ORCID 0000-0001-9423-4032
Tzahi Cohen-KarniDepartment of Materials Science and Engineering and Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.ORCID 0000-0001-5742-1007

Funding

Mechanisms of Pain Associated with Trigeminal Nerve InjuryR01NS122784 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOLD, MICHAEL S, SEKULA, RAYMOND F · 2021 to 2025
$2.8M
Validating MXene Electrodes for Next-Generation ElectroencephalographyR01NS121219 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI MEDAGLIA, JOHN, VITALE, FLAVIA · 2021 to 2025
$2.3M
Hybrid-nanomaterials for non-genetic optical stimulation of excitable cellsR21EB029164 · NIBIB · CARNEGIE-MELLON UNIVERSITY · PI COHEN-KARNI, TZAHI · 2020 to 2021
$397k
Department of Materials Science and Engineering Materials Characterization Facility MCF-677785NIBIB NIH HHS R21 EB029164NIH HHS R01 NS122784NIH HHS R21EB029164NINDS NIH HHS R01 NS121219NINDS NIH HHS R01NS121219NINDS NIH HHS R01 NS122784
6 · The paper itself

Abstract

Understanding the communication of individual neurons necessitates precise control of neural activity. Photothermal modulation is a remote and non-genetic technique to control neural activity with high spatiotemporal resolution. The local heat release by photothermally active nanomaterial will change the membrane properties of the interfaced neurons during light illumination. Recently, it is demonstrated that the two-dimensional Ti

Indexed as

NeuronsOxidative StressAnimalsCell MembraneNanostructuresRatsTitaniumTitaniumbiosafetydorsal root ganglionneuronsphotothermal modulationphototoxicityTi3C2Tx MXene

Identifiers

PMID37755313
PMCPMC10963341

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.