Evidence map›Paper›PMID 37755292›Full record

ArticleMetabolites2023

Stable Isotope Dilution Analysis (SIDA) to Determine Metabolites of Furan and 2-Methylfuran in Human Urine Samples: A Pilot Study.

Jonathan Isaak Kremer, Dorothea Karlstetter, Verena Kirsch, Daniel Bohlen, Carina Klier, Jan Rotermund, Hannah Thomas, Lukas Lang, Hanna Becker, Tamara Bakuradze and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Jonathan Isaak KremerDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Dorothea KarlstetterDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Verena KirschDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Daniel BohlenDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Carina KlierDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Jan RotermundDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Hannah ThomasDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Lukas LangDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Hanna BeckerDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Tamara BakuradzeDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Simone StegmüllerDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.
Elke RichlingDepartment of Chemistry, Division of Food Chemistry and Toxicology, RPTU Kaiserslautern-Landau, Erwin-Schrödinger-Str. 52, D-67663 Kaiserslautern, Germany.ORCID 0000-0001-5746-8032
Rheinland-Pfälzische Technische Universität Kaiserslautern-Landau · DE

Funding

Deutsche Forschungsgemeinschaft RI 1176/12-1Deutsche Forschungsgemeinschaft RI 1176/13-1
6 · The paper itself

Abstract

Furan and 2-methylfuran (2-MF) are food contaminants that are classified as potentially carcinogenic to humans. The main source of exposure for adults via food is coffee consumption. Furan and 2-MF are volatile, which complicates exposure assessment because their content measured in food prior to consumption does not afford a reliable dosimetry. Therefore, other ways of exposure assessment need to be developed, preferably by monitoring exposure biomarkers, e.g., selected metabolites excreted in urine. In this study,

Indexed as

2-methylfuran3-acetyl acroleincis-2-buten-1,4-dialcoffeefuranmetabolismSIDAtoxicokinetic

Identifiers

PMID37755292
PMCPMC10535680
OpenAlexW4386780388

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.