Evidence map›Paper›PMID 37755129›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2023

Processing DNA Storage through Programmable Assembly in a Droplet-Based Fluidics System.

Minsang Yu, Doyeon Lim, Jungwoo Kim, Youngjun Song

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. DNA storage: The future direction for medical cold data storage.Synthetic and systems biotechnology · 2025
    Review
  4. Breast Tumor Diagnosis Based on Molecular Learning Vector Quantization Neural Networks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  5. Article
  6. Inert splint-driven oligonucleotide assembly.Synthetic biology (Oxford, England) · 2024
    Article
  7. Processing DNA Storage through Programmable Assembly in a Droplet-Based Fluidics System.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Minsang YuStandard Bioelectronics. Co., 511 Michuhol Tower, Gaetbeol-ro 12, Incheon, 21999, South Korea.
Doyeon LimDepartment of Nano-Bioengineering, Incheon National University, Academy-ro 119, Incheon, 22012, South Korea.
Jungwoo KimDepartment of Nano-Bioengineering, Incheon National University, Academy-ro 119, Incheon, 22012, South Korea.
Youngjun SongStandard Bioelectronics. Co., 511 Michuhol Tower, Gaetbeol-ro 12, Incheon, 21999, South Korea.ORCID 0000-0001-9423-6169

Funding

National Research Foundation of Korea NRF-2021R1A4A3031992National Research Foundation of Korea NRF-2021R1C1C1009300
6 · The paper itself

Abstract

DNA can be used to store digital data, and synthetic short-sequence DNA pools are developed to store high quantities of digital data. However, synthetic DNA data cannot be actively processed in DNA pools. An active DNA data editing process is developed using splint ligation in a droplet-controlled fluidics (DCF) system. DNA fragments of discrete sizes (100-500 bps) are synthesized for droplet assembly, and programmed sequence information exchange occurred. The encoded DNA sequences are processed in series and parallel to synthesize the determined DNA pools, enabling random access using polymerase chain reaction amplification. The sequencing results of the assembled DNA data pools can be orderly aligned for decoding and have high fidelity through address primer scanning. Furthermore, eight 90 bps DNA pools with pixel information (png: 0.27-0.28 kB), encoded by codons, are synthesized to create eight 270 bps DNA pools with an animation movie chip file (mp4: 12 kB) in the DCF system.

Indexed as

DNAPolymerase Chain ReactionDNAaddress primer scanningDNA data storagedroplet-controlled fluidics systemprocessing of DNA storagesplint ligation

Identifiers

PMID37755129
PMCPMC10646262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.