Evidence map›Paper›PMID 37755074›Full record

ReviewMarine drugs2023

Sulfated Polysaccharides from Seaweeds: A Promising Strategy for Combatting Viral Diseases-A Review.

N M Liyanage, D P Nagahawatta, Thilina U Jayawardena, Kalu Kapuge Asanka Sanjeewa, H H A C K Jayawrdhana, Jae-Il Kim, You-Jin Jeon

Open access · goldAbstract readReview
In one paragraph

Review in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Alternating High-Fat and Polysaccharide Diets Modulates Gut Phage-Bacterial Interplay.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

N M LiyanageDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.
D P NagahawattaDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.
Thilina U JayawardenaDépartement of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, QC G8Z 4M3, Canada.ORCID 0000-0002-4303-8282
Kalu Kapuge Asanka SanjeewaDepartment of Biosystems Technology, Faculty of Technology, University of Sri Jayewardenepura, Pitipana 10206, Sri Lanka.ORCID 0000-0001-7073-995X
H H A C K JayawrdhanaDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.
Jae-Il KimDepartment of Food Science & Nutrition, Pukyong National University, Busan 48513, Republic of Korea.ORCID 0000-0002-6186-5492
You-Jin JeonDepartment of Marine Life Sciences, Jeju National University, Jeju 63243, Republic of Korea.ORCID 0000-0003-3299-7266
Jeju National University · KRPukyong National University · KRUniversité du Québec à Trois-Rivières · CAUniversity of Sri Jayewardenepura · LK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The limited availability of treatments for many infectious diseases highlights the need for new treatments, particularly for viral infections. Natural compounds from seaweed are attracting increasing attention for the treatment of various viral diseases, and thousands of novel compounds have been isolated for the development of pharmaceutical products. Seaweed is a rich source of natural bioactive compounds, including polysaccharides. The discovery of algal polysaccharides with antiviral activity has significantly increased in the past few decades. Furthermore, unique polysaccharides isolated from seaweeds, such as carrageenan, alginates, fucoidans, galactans, laminarians, and ulvans, have been shown to act against viral infections. The antiviral mechanisms of these agents are based on their inhibition of DNA or RNA synthesis, viral entry, and viral replication. In this article, we review and provide an inclusive description of the antiviral activities of algal polysaccharides. Additionally, we discuss the challenges and opportunities for developing polysaccharide-based antiviral therapies, including issues related to drug delivery and formulation. Finally, this review highlights the need for further research for fully understanding the potential of seaweed polysaccharides as a source of antiviral agents and for developing effective treatments for viral diseases.

Indexed as

Antiviral AgentsPolysaccharidesSeaweedSulfuric Acid EstersAnimalsHumansSARS-CoV-2Antiviral AgentsPolysaccharidesSulfuric Acid Estersantiviral activityantiviral compoundsbioactive compoundsDNA synthesis inhibitormarine algaemarine natural productsvirus

Identifiers

PMID37755074
PMCPMC10532895
OpenAlexW4386091944

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.