ReviewJournal of fungi (Basel, Switzerland)2023
The Enigmatic World of Fungal Melanin: A Comprehensive Review.
Review in Journal of fungi (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed.
- The complex subunit VdAP-2α regulates polar growth, ergosterol metabolism, and virulence inVirulence · 2026Article
- Fungal melanin as a bioactive biopolymer: structural diversity, oxidative stress modulation, anticancer mechanisms, and therapeutic perspectives.RSC advances · 2026Review
- Toxicological Assessment and Dual Protective Roles ofJournal of fungi (Basel, Switzerland) · 2026Article
- Article
- Nutrient utilization and degradative enzyme activity of the dragon fruit canker pathogen,Microbiology (Reading, England) · 2026Article
- Dismantling darkness: interdisciplinary perspectives on melanin degradation.World journal of microbiology & biotechnology · 2026Review
- Antioxidants: Mechanisms, Benefits, and the Importance of Extremophilic Microorganisms.Microorganisms · 2026Review
- Exploring allomelanin: A comparative analysis via natural product extraction and synthesis.Science advances · 2026Article
- Integrated LC-HRMS and HPLC Profiling of Fourteen AnatolianPharmaceuticals (Basel, Switzerland) · 2026Article
- Review
- Methods for evaluating bacterial dispersal on hyphal networks.microLife · 2026Article
- Melanin and Neuromelanin in Humans: Insights Across Health, Aging, Diseases, and Unexpected Aspects of Fungal Melanogenesis.Biomolecules · 2025Review
- Unravelling the Potential of Fungal Division of Labour in the Laccase ProducerJournal of fungi (Basel, Switzerland) · 2025Article
- Melanin biosynthesis and functional roles in insects: insights into immunological defense, physiological regulation, and environmental adaptation.Annals of medicine and surgery (2012) · 2025Review
- Edible Fungi Melanin: Recent Advances in Extraction, Characterization, Biological Activity and Applications.Journal of fungi (Basel, Switzerland) · 2025Review
- Filamentous fungal-mediated melanin nanoparticles for heavy metal detoxification via bioadsorption: a sustainable approach.Biodegradation · 2025Article
- Isolation and Structural Characterization of Melanins from Red and Yellow Varieties ofInternational journal of molecular sciences · 2025Article
- Fungal Melanin in Plant Pathogens: Complex Biosynthesis Pathways and Diverse Biological Functions.Plants (Basel, Switzerland) · 2025Review
- Green Processes for Chitin and Chitosan Production from Insects: Current State, Challenges, and Opportunities.Polymers · 2025Review
- Fungal Metabolomics: A Comprehensive Approach to Understanding Pathogenesis in Humans and Identifying Potential Therapeutics.Journal of fungi (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Synthetic dyes are generally not safe for human health or the environment, leading to the continuous search and growing demand for natural pigments that are considered safer, biodegrade more easily, and are environmentally beneficial. Among micro-organisms, fungi represent an emerging source of pigments due to their many benefits; therefore, they are readily viable on an industrial scale. Among all the bioactive pigments produced by fungi, melanin is an enigmatic, multifunctional pigment that has been studied for more than 150 years. This dark pigment, which is produced via the oxidative polymerization of phenolic compounds, has been investigated for its potential to protect life from all kingdoms, including fungi, from biotic and abiotic stresses. Over time, the research on fungal melanin has attracted a significant amount of scientific interest due to melanin's distinct biological activities and multifarious functionality, which is well-documented in the literature and could possibly be utilized. This review surveys the literature and summarizes the current discourse, presenting an up-to-date account of the research performed on fungal melanin that encompasses its types, the factors influencing its bioactivity, the optimization of fermentation conditions to enhance its sustainable production, its biosynthetic pathways, and its extraction, as well as biochemical characterization techniques and the potential uses of melanin in a wide range of applications in various industries. A massive scope of work remains to circumvent the obstacles to obtaining melanin from fungi and exploring its future prospects in a diverse range of applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.