Evidence map›Paper›PMID 37754987›Full record

ArticleJournal of fungi (Basel, Switzerland)2023

High-Throughput Screening of the Repurposing Hub Library to Identify Drugs with Novel Inhibitory Activity against

Olabayo H Ajetunmobi, Gina Wall, Bruna Vidal Bonifacio, Lucero A Martinez Delgado, Ashok K Chaturvedi, Laura K Najvar, Floyd L Wormley, Hoja P Patterson, Nathan P Wiederhold, Thomas F Patterson and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of fungi (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Drug Discovery and Repurposing forJournal of fungi (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Olabayo H AjetunmobiDepartment of Molecular Microbiology & Immunology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA.
Gina WallDepartment of Molecular Microbiology & Immunology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA.
Bruna Vidal BonifacioDepartment of Molecular Microbiology & Immunology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA.
Lucero A Martinez DelgadoDepartment of Healthcare Sciences, University of The Incarnate Word, San Antonio, TX 78209, USA.
Ashok K ChaturvediDepartment of Molecular Microbiology & Immunology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA.
Laura K NajvarDepartment of Medicine, Division of Infectious Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Floyd L WormleyDepartment of Biology, Texas Christian University, Fort Worth, TX 76129, USA.
Hoja P PattersonDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.
Nathan P WiederholdDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.ORCID 0000-0002-2225-5122
Thomas F PattersonDepartment of Medicine, Division of Infectious Diseases, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.ORCID 0000-0002-9513-7127
Jose L Lopez-RibotDepartment of Molecular Microbiology & Immunology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA.ORCID 0000-0003-1992-3270

Funding

Screening a Target-Based Repurposing Library for Activity against Fungal Pathogens and Subsequent Preclinical Development of Leading CandidatesR33AI140823 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI LOPEZ-RIBOT, JOSE L., WORMLEY, FLOYD L. · 2021 to 2023
$1.3M
High Throughput Screening of Medicines for Malaria Ventures Chemical Libraries to Identify Novel Inhibitors of Candida aurisR21AI156100 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI LOPEZ-RIBOT, JOSE L. · 2021 to 2022
$413k
NIAID NIH HHS R21 AI156100NIAID NIH HHS R33 AI140823
6 · The paper itself

Abstract

Candidiasis is one of the most frequent nosocomial infections affecting an increasing number of at-risk patients.

Indexed as

antifungalbiofilmCandida spp.repurposingscreening

Identifiers

PMID37754987
PMCPMC10532723

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.