Evidence map›Paper›PMID 37754889›Full record

ArticleJournal of functional biomaterials2023

Biological Performance of Duplex PEO + CNT/PCL Coating on AZ31B Mg Alloy for Orthopedic and Dental Applications.

Morteza Daavari, Masoud Atapour, Marta Mohedano, Endzhe Matykina, Raul Arrabal, Dobrila Nesic

Open access · goldAbstract read
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Morteza DaavariDepartment of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran.
Masoud AtapourDepartment of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran.ORCID 0000-0001-6333-0179
Marta MohedanoDepartamento de Ingeniería Química y de Materiales, Facultad de Ciencias Químicas, Universidad Complutense, 28040 Madrid, Spain.ORCID 0000-0002-9318-3031
Endzhe MatykinaDepartamento de Ingeniería Química y de Materiales, Facultad de Ciencias Químicas, Universidad Complutense, 28040 Madrid, Spain.
Raul ArrabalDepartamento de Ingeniería Química y de Materiales, Facultad de Ciencias Químicas, Universidad Complutense, 28040 Madrid, Spain.ORCID 0000-0002-7649-4049
Dobrila NesicDivision of Fixed Prosthodontics and Biomaterials, University Clinic of Dental Medicine, University of Geneva, Rue Michel-Servet 1, CH-1211 Geneva, Switzerland.ORCID 0000-0003-1609-9255
Universidad Complutense de Madrid · ESIsfahan University of Technology · IRUniversity of Geneva · CH

Funding

ADITIMAT-CM Regional Government of Madrid and EU Structural Funds S2018/NMT-4411Avicenna Center of Excellence (ACE) no grant numberIsfahan Research Network no grant numberMCIU/AEI/FEDER, UE PID2021-124341OB-C22Ministerio de Ciencia e Innovación RYC-2017-21843
6 · The paper itself

Abstract

To regulate the degradation rate and improve the surface biocompatibility of the AZ31B magnesium alloy, three different coating systems were produced via plasma electrolytic oxidation (PEO): simple PEO, PEO incorporating multi-walled carbon nanotubes (PEO + CNT), and a duplex coating that included a polycaprolactone top layer (PEO + CNT/PCL). Surfaces were characterized by chemical content, roughness, topography, and wettability. Biological properties analysis included cell metabolism and adhesion. PEO ± CNT resulted in an augmented surface roughness compared with the base material (BM), while PCL deposition produced the smoothest surface. All surfaces had a contact angle below 90°. The exposure of gFib-TERT and bmMSC to culture media collected after 3 or 24 h did not affect their metabolism. A decrease in metabolic activity of 9% and 14% for bmMSC and of 14% and 29% for gFib-TERT was observed after 3 and 7 days, respectively. All cells died after 7 days of exposure to BM and after 15 days of exposure to coated surfaces. Saos-2 and gFib-TERT adhered poorly to BM, in contrast to bmMSC. All cells on PEO anchored into the pores with filopodia, exhibited tiny adhesion protrusions on PEO + CNT, and presented a web-like spreading with lamellipodia on PEO + CNT/PCL. The smooth and homogenous surface of the duplex PEO + CNT/PCL coating decreased magnesium corrosion and led to better biological functionality.

Indexed as

biodegradable Mg-based implantcell adhesioncell metabolismmulti-walled carbon nanotubes (MWCNT)plasma electrolyte oxidation (PEO)polycaprolactone (PCL)

Identifiers

PMID37754889
PMCPMC10532417
OpenAlexW4386837364

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.