Evidence map›Paper›PMID 37754449›Full record

ReviewGels (Basel, Switzerland)2023

From Free Tissue Transfer to Hydrogels: A Brief Review of the Application of the Periosteum in Bone Regeneration.

Hai Xin, Eva Tomaskovic-Crook, D S Abdullah Al Maruf, Kai Cheng, James Wykes, Timothy G H Manzie, Steven G Wise, Jeremy M Crook, Jonathan R Clark

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hai XinIntegrated Prosthetics and Reconstruction, Department of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.ORCID 0000-0002-6914-3910
Eva Tomaskovic-CrookArto Hardy Family Biomedical Innovation Hub, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.ORCID 0000-0002-7818-9013
D S Abdullah Al MarufIntegrated Prosthetics and Reconstruction, Department of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.ORCID 0000-0001-8573-4035
Kai ChengIntegrated Prosthetics and Reconstruction, Department of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.ORCID 0000-0001-6435-4375
James WykesIntegrated Prosthetics and Reconstruction, Department of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.
Timothy G H ManzieIntegrated Prosthetics and Reconstruction, Department of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.ORCID 0000-0001-9171-9878
Steven G WiseSchool of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2006, Australia.ORCID 0000-0001-7964-819X
Jeremy M CrookArto Hardy Family Biomedical Innovation Hub, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.ORCID 0000-0002-6415-1639
Jonathan R ClarkIntegrated Prosthetics and Reconstruction, Department of Head and Neck Surgery, Chris O'Brien Lifehouse, Camperdown, NSW 2050, Australia.ORCID 0000-0003-1209-772X

Funding

National Heart Foundation Future Leader Fellowship N/ANational Heart Foundation Vanguard Grant N/ASydney Local Health District N/AThe Arto Hardy Family N/AThe Australia and New Zealand Head and Neck Cancer Society N/AThe Cancer Institute New South Wales CINSW 2020/2081The Lang Walker Family Foundation N/AThe SurFebruary Cancer Research Fund N/A
6 · The paper itself

Abstract

The periosteum is a thin layer of connective tissue covering bone. It is an essential component for bone development and fracture healing. There has been considerable research exploring the application of the periosteum in bone regeneration since the 19th century. An increasing number of studies are focusing on periosteal progenitor cells found within the periosteum and the use of hydrogels as scaffold materials for periosteum engineering and guided bone development. Here, we provide an overview of the research investigating the use of the periosteum for bone repair, with consideration given to the anatomy and function of the periosteum, the importance of the cambium layer, the culture of periosteal progenitor cells, periosteum-induced ossification, periosteal perfusion, periosteum engineering, scaffold vascularization, and hydrogel-based synthetic periostea.

Indexed as

3-D printingcambium layerhydrogelsossificationperiosteumprogenitor cellssynthetic periosteum

Identifiers

PMID37754449
PMCPMC10530949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.