Evidence map›Paper›PMID 37754434›Full record

ReviewGels (Basel, Switzerland)2023

The Application of Nanogels as Efficient Drug Delivery Platforms for Dermal/Transdermal Delivery.

Panoraia I Siafaka, Ece Özcan Bülbül, Mehmet Evren Okur, Ioannis D Karantas, Neslihan Üstündağ Okur

Abstract readReview
In one paragraph

Review in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
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  5. Application of chitosan-based nanogels for dermal and transdermal delivery systems.Journal of materials science. Materials in medicine · 2025
    Review
  6. Article
  7. Review
  8. Review
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  10. Review
  11. Article
  12. Review
  13. Unassuming Lichens: Nature's Hidden Antimicrobial Warriors.International journal of molecular sciences · 2025
    Review
  14. Review
  15. Review
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  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Panoraia I SiafakaDepartment of Life Sciences, School of Sciences, Faculty of Pharmacy, European University Cyprus, 2404 Nicosia, Cyprus.ORCID 0000-0001-7256-3230
Ece Özcan BülbülDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Istinye University, 34010 Istanbul, Turkey.ORCID 0000-0001-7112-923X
Mehmet Evren OkurDepartment of Pharmacology, Faculty of Pharmacy, University of Health Sciences, 34116 Istanbul, Turkey.
Ioannis D KarantasApostolos Loukas Medical Centre, 2415 Nicosia, Cyprus.
Neslihan Üstündağ OkurDepartment of Pharmaceutical Technology, Faculty of Pharmacy, University of Health Sciences, 34668 Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The delivery of active molecules via the skin seems to be an efficient technology, given the various disadvantages of oral drug administration. Skin, which is the largest human organ of the body, has the important role of acting as a barrier for pathogens and other molecules including drugs; in fact, it serves as a primary defense system blocking any particle from entering the body. Therefore, to overcome the skin barriers and poor skin permeability, researchers implement novel carriers which can effectively carry out transdermal delivery of the molecules. Another significant issue which medical society tries to solve is the effective dermal delivery of molecules especially for topical wound delivery. The application of nanogels is only one of the available approaches offering promising results for both dermal and transdermal administration routes. Nanogels are polymer-based networks in nanoscale dimensions which have been explored as potent carriers of poorly soluble drugs, genes and vaccines. The nanogels present unique physicochemical properties, i.e., high surface area, biocompatibility, etc., and, importantly, can improve solubility. In this review, authors aimed to summarize the available applications of nanogels as possible vehicles for dermal and transdermal delivery of active pharmaceutical ingredients and discuss their future in the pharmaceutical manufacturing field.

Indexed as

cross-linkingdeliverydermalnanogelsresponsiveskintransdermal

Identifiers

PMID37754434
PMCPMC10529964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.