Evidence map›Paper›PMID 37754412›Full record

ArticleGels (Basel, Switzerland)2023

In Situ Forming Bioartificial Hydrogels with ROS Scavenging Capability Induced by Gallic Acid Release with Potential in Chronic Skin Wound Treatment.

Rossella Laurano, Alessandro Torchio, Gianluca Ciardelli, Monica Boffito

Abstract read
In one paragraph

Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
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  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rossella LauranoDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0003-3018-603X
Alessandro TorchioDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino, Italy.
Gianluca CiardelliDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0003-0199-1427
Monica BoffitoDepartment of Mechanical and Aerospace Engineering, Politecnico di Torino, 10129 Torino, Italy.ORCID 0000-0001-7637-2001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In normal chronic wound healing pathways, the presence of strong and persistent inflammation states characterized by high Reactive Oxygen Species (ROS) concentrations is one of the major concerns hindering tissue regeneration. The administration of different ROS scavengers has been investigated over the years, but their effectiveness has been strongly limited by their short half-life caused by chronic wound environmental conditions. This work aimed at overcoming this criticism by formulating bioartificial hydrogels able to preserve the functionalities of the encapsulated scavenger (i.e., gallic acid-GA) and expand its therapeutic window. To this purpose, an amphiphilic poly(ether urethane) exposing -NH groups (4.5 × 10

Indexed as

amphiphilic poly(ether urethane)sbioartificial hydrogelsdrug delivery carriersgallic acidintracellular ROS measurementsROS scavengingthermo-sensitive formulations

Identifiers

PMID37754412
PMCPMC10529965

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.