Evidence map›Paper›PMID 37754317›Full record

ReviewDiseases (Basel, Switzerland)2023

Lipschütz Ulcer and SARS-CoV-2: What We Currently Know?

Lucia Merlino, Agnese Immacolata Volpicelli, Mattia Dominoni, Marianna Francesca Pasquali, Giulia D'Ovidio, Barbara Gardella, Roberto Senatori

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Diseases (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lucia MerlinoDepartment of Medical-Surgical Sciences and Biotechnologies, Sapeinza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-4281-8308
Agnese Immacolata VolpicelliDepartment of Medical-Surgical Sciences and Biotechnologies, Sapeinza University of Rome, 00161 Rome, Italy.
Mattia DominoniDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-6322-607X
Marianna Francesca PasqualiDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-3744-7888
Giulia D'OvidioDepartment of Medical-Surgical Sciences and Biotechnologies, Sapeinza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-7669-5430
Barbara GardellaDepartment of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-0812-8995
Roberto SenatoriItalian Society of Colposcopy and Cervicovaginal Pathology (SICPV), 00186 Rome, Italy.
Sapienza University of Rome · ITUniversity of Pavia · ITSocietà Italiana di Cardiologia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn recent years, several interesting case reports have been published which describe the possible role of SARS-CoV-2 infection or vaccination in the etiopathogenesis of Lipschütz ulcer. Our aim is to analyze this association and provide a rapid algorithm that is of support to gynecologists and dermatologists both in the diagnosis and in setting up the therapy. To do so, in this paper, we describe an interesting case of acute vulvar ulcer triggered by SARS-CoV-2 infection and review the related literature.

methodsWe conducted a literature review including papers published between October 2021 and April 2023, and we described the case of a patient referred to our clinic with Lipschütz ulcer and SARS-CoV-2 infection.

resultsIn almost all cases analyzed, a correlation with SARS-CoV-2 infection or vaccination was found; ulcers usually manifest after 2 to 4 weeks and are associated with flu-like symptoms. A concordance in review papers, as well as in our case report, was also found about the treatment, which is mainly symptomatic.

conclusionsPrevious infection or vaccination for SARS-CoV-2 should be included as possible etiopathogenetic factors in the onset of Lipschütz ulcer.

Indexed as

acute vulvar ulcerCOVID-19Lipschütz ulcernon-sexually transmitted vulvar aphthosisSARS-CoV-2

Identifiers

PMID37754317
PMCPMC10528082
OpenAlexW4386715034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.