Evidence map›Paper›PMID 37754092›Full record

ArticleBiosensors2023

Heterogeneous-Nucleation Biosensor for Long-Term Collection and Mask-Based Self-Detection of SARS-CoV-2.

Yi Su, Sumin Bian, Dingyi Pan, Yankun Xu, Guoguang Rong, Hongyong Zhang, Mohamad Sawan

Abstract read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yi SuCollege of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou 310013, China.
Sumin BianCenBRAIN Neurotech, School of Engineering, Westlake University, Hangzhou 310030, China.ORCID 0000-0002-9470-8143
Dingyi PanCollege of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou 310013, China.ORCID 0000-0002-4804-2942
Yankun XuCenBRAIN Neurotech, School of Engineering, Westlake University, Hangzhou 310030, China.ORCID 0000-0002-4410-4106
Guoguang RongCenBRAIN Neurotech, School of Engineering, Westlake University, Hangzhou 310030, China.ORCID 0000-0001-6824-9900
Hongyong ZhangCenBRAIN Neurotech, School of Engineering, Westlake University, Hangzhou 310030, China.ORCID 0000-0001-6364-6448
Mohamad SawanCenBRAIN Neurotech, School of Engineering, Westlake University, Hangzhou 310030, China.ORCID 0000-0002-4137-7272

Funding

Zhejiang Key R&D Program Project No. 2021C03002Zhejiang Leading Innovative and Entrepreneur Team Introduction Program No. 2020R01005
6 · The paper itself

Abstract

The effective control of infectious diseases, including Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, depends on the availability of rapid and accurate monitoring techniques. However, conventional SARS-CoV-2 detection technologies do not support continuous self-detection and may lead to cross-infection when utilized in medical institutions. In this study, we introduce a prototype of a mask biosensor designed for the long-term collection and self-detection of SARS-CoV-2. The biosensor utilizes the average resonance Rayleigh scattering intensity of Au nanocluster-aptamers. The inter-mask surface serves as a medium for the long-term collection and concentration enhancement of SARS-CoV-2, while the heterogeneous-nucleation nanoclusters (NCs) contribute to the exceptional stability of Au NCs for up to 48 h, facilitated by the adhesion of Ti NCs. Additionally, the biosensors based on Au NC-aptamers exhibited high sensitivity for up to 1 h. Moreover, through the implementation of a support vector machine classifier, a significant number of point signals can be collected and differentiated, leading to improved biosensor accuracy. These biosensors offer a complementary wearable device-based method for diagnosing SARS-CoV-2, with a limit of detection of 10

Indexed as

Biosensing TechniquesCOVID-19SARS-CoV-2GoldHumansMasksMetal NanoparticlesSupport Vector MachineWearable Electronic DevicesGoldAu NCsbiosensorsCOVID-19heterogeneous nucleationmaskSARS-CoV-2

Identifiers

PMID37754092
PMCPMC10526364

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.