ArticleBiosensors2023
Flux-Type versus Concentration-Type Sensors in Transdermal Measurements.
Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Nanoemulgels as Advanced Topical Drug Delivery Systems: Mechanistic Insights and Therapeutic Applications in Skin Disorders, Infections, Wound Healing, and Cancer.Pharmaceuticals (Basel, Switzerland) · 2026Review
- Update on Patient Self-Testing with Portable and Wearable Devices: Advantages and Limitations.Diagnostics (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
New transdermal biosensors measure analytes that diffuse from the bloodstream through the skin, making it important to reduce the system response time and understand measurement output. While highly customized models have been created for specific sensors, a generalized model for transdermal sensor systems is lacking. Here, a simple one-dimensional diffusion model was used to characterize the measurement system and classify biosensors as either flux types or concentration types. Results showed that flux-type sensors have significantly faster response times than concentration sensors. Furthermore, flux sensors do not measure concentration, but rather have an output measurement that is proportional to skin permeability. These findings should lead to an improved understanding of transdermal measurements and their relation to blood analyte concentration. In the realm of alcohol research, where the majority of commercially available sensors are flux types, our work advocates toward moving away from transdermal alcohol concentration as a metric, and instead suggests embracing transdermal alcohol flux as a more suitable alternative.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.