Evidence map›Paper›PMID 37753673›Full record

ReviewSkin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)2023

Recent advances in exosomal non-coding RNA-based therapeutic approaches for photoaging.

Kun-Jie Li, Peng-Jun Zhou, Yan-Ni Guo, Tian-Xing Xu, Song-Fa Lin, Shu Lin, Chao Ji

Open access · hybridAbstract readReview
In one paragraph

Review in Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Skin boosters: Definitions and varied classifications.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Review
  9. Recent advances in exosomal non-coding RNA-based therapeutic approaches for photoaging.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Review
  10. Exploring the reality of exosomes in dermatology.Anais brasileiros de dermatologia
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Kun-Jie LiDepartment of Dermatology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.ORCID https://orcid.org/0000-0001-6100-9920
Peng-Jun ZhouDepartment of Dermatology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
Yan-Ni GuoDepartment of Dermatology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
Tian-Xing XuDepartment of Dermatology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
Song-Fa LinDepartment of Dermatology, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
Shu LinCentre of Neurological and Metabolic Research, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.
Chao JiDepartment of Dermatology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian, China.
Fujian Medical University · CN

Funding

linshuScience and Technology Bureau of Quanzhou 2020CT003
6 · The paper itself

Abstract

backgroundPhotoaging is a degenerative biological process that affects the quality of life. It is caused by environmental factors including ultraviolet radiation (UVR), deep skin burns, smoking, active oxygen, chemical substances, and trauma. Among them, UVR plays a vital role in the aging process.

aimWith the continuous development of modern medicine, clinical researchers have investigated novel approaches to treat aging. In particular, mesenchymal stem cells (MSCs), non-coding RNAs are involved in various physiological processes have broad clinical application as they have the advantages of convenient samples, abundant sources, and avoidable ethical issues.

methodsThis article reviews research progress on five types of stem cell, exosomes, non-coding RNA in the context of photoaging treatment: adipose-derived stem cell, human umbilical cord MSCs, epidermal progenitor cells, keratinocyte stem cells, and hair follicle stem cells (HFSCs). It also includes stem cell related exosomes and their non-coding RNA research.

resultsThe results have clinical guiding significance for prevention and control of the onset and development of photoaging. It is found that stem cells secrete cytokines, cell growth factors, non-coding RNA, exosomes and proteins to repair aging skin tissues and achieve skin rejuvenation. In particular, stem cell exosomes and non-coding RNA are found to have significant research potential, as they possess the benefits of their source cells without the disadvantages which include immune rejection and granuloma formation.

Indexed as

Skin AgingHumansQuality of LifeRNA, UntranslatedSkinUltraviolet RaysRNA, Untranslatedexosomemesenchymal stem cellsnon-coding RNAphotoagingskin cancerultraviolet radiation

Identifiers

PMID37753673
PMCPMC10495620
OpenAlexW4386640823

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.