Evidence map›Paper›PMID 37753490›Full record

ReviewWorld journal of clinical pediatrics2023

Role of gastrointestinal health in managing children with autism spectrum disorder.

Mohammed Al-Beltagi, Nermin Kamal Saeed, Adel Salah Bediwy, Reem Elbeltagi, Rawan Alhawamdeh

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of clinical pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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  17. Novel mouse line with D277N mutation in theFrontiers in cell and developmental biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Mohammed Al-BeltagiPediatric Department, Faculty of Medicine, Tanta University, Algharbia, Tanta ‎31511‎, Egypt.
Nermin Kamal SaeedMedical Microbiology Section, Pathology Department‎, Salmaniya Medical Complex, Ministry of Health‎, Manama, Manama 12, Bahrain.
Adel Salah BediwyPulmonology Department‎, Faculty of Medicine, Tanta University‎, Algharbia, Tanta ‎31527‎, Egypt.
Reem ElbeltagiMedicine, The Royal College of Surgeons in Ireland-Bahrain‎, Muharraq, Busiateen 15503, Bahrain.
Rawan AlhawamdehPediatrics Research, and Development Department‎, Genomics Creativity and Play Center, Manama, Manama 0000, Bahrain.
Royal College of Surgeons in Ireland - Bahrain · BHTanta University · EGDubai Hospital · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Children with autism spectrum disorders (ASD) or autism are more prone to gastrointestinal (GI) disorders than the general population. These disorders can significantly affect their health, learning, and development due to various factors such as genetics, environment, and behavior. The causes of GI disorders in children with ASD can include gut dysbiosis, immune dysfunction, food sensitivities, digestive enzyme deficiencies, and sensory processing differences. Many studies suggest that numerous children with ASD experience GI problems, and effective management is crucial. Diagnosing autism is typically done through genetic, neurological, functional, and behavioral assessments and observations, while GI tests are not consistently reliable. Some GI tests may increase the risk of developing ASD or exacerbating symptoms. Addressing GI issues in individuals with ASD can improve their overall well-being, leading to better behavior, cognitive function, and educational abilities. Proper management can improve digestion, nutrient absorption, and appetite by relieving physical discomfort and pain. Alleviating GI symptoms can improve sleep patterns, increase energy levels, and contribute to a general sense of well-being, ultimately leading to a better quality of life for the individual and improved family dynamics. The primary goal of GI interventions is to improve nutritional status, reduce symptom severity, promote a balanced mood, and increase patient independence.

Indexed as

Autism spectrum disorders, ChildrenGastrointestinal disordersGluten-free casein-free diet, Dietary managementGut microbiotaKetogenic diet

Identifiers

PMID37753490
PMCPMC10518744
OpenAlexW4386455768

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.