Evidence map›Paper›PMID 37753364›Full record

ReviewFuture science OA2023

Pushing the frontiers in the fight against antimicrobial resistance: the potential of fecal and maggot therapies.

Bashar Haruna Gulumbe, Abdulrakib Abdulrahim

Open access · goldAbstract readReview
In one paragraph

Review in Future science OA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bashar Haruna GulumbeDepartment of Microbiology, Faculty of Science, Federal University, Kalgo, Birnin Kebbi, PMB, 1157, Nigeria.ORCID https://orcid.org/0000-0003-0642-6902
Abdulrakib AbdulrahimDepartment of Microbiology, Faculty of Science, Federal University, Kalgo, Birnin Kebbi, PMB, 1157, Nigeria.ORCID https://orcid.org/0000-0002-2939-7086
Federal University Birnin Kebbi · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The escalating crisis of antimicrobial resistance (AMR) warrants innovative therapeutic strategies. Fecal microbiota transplantation (FMT) and maggot debridement therapy (MDT) represent paradigm-shifting approaches, leveraging biological systems to mitigate AMR. FMT restores a healthy gut microbiome, providing a biotherapeutic counter to pathogenic bacteria, thereby reducing reliance on traditional antibiotics. Conversely, MDT, a form of bio-debridement, utilizes the antimicrobial secretions of maggots to cleanse wounds and eliminate resistant bacteria. Despite the promise these therapies hold, their broader clinical adoption faces multifaceted challenges including the need for rigorous scientific substantiation, standardized protocols, deepened understanding of mechanisms of action, and surmounting regulatory and public acceptance barriers. However, their potential integration with precision medicine could revolutionize disease management, particularly with antibiotic-resistant infections.

Indexed as

antimicrobial resistancebiotherapeuticsfecal microbiota transplantationgut microbiomemaggot debridement therapy

Identifiers

PMID37753364
PMCPMC10518815
OpenAlexW4386255493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.