Evidence map›Paper›PMID 37753357›Full record

ArticleFuture science OA2023

Prognostic performance of pretreatment systemic immune-inflammation index in women with epithelial ovarian cancer.

Kehinde S Okunade, Sarah O John-Olabode, Adaiah P Soibi-Harry, Austin C Okoro, Adebola A Adejimi, Iyabo Y Ademuyiwa, Benedetto Osunwusi, Hameed Adelabu, Omolola Salako

Abstract read
In one paragraph

Article in Future science OA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kehinde S OkunadeDepartment of Obstetrics & Gynaecology, College of Medicine, University of Lagos, Surulere, Lagos, Nigeria.ORCID https://orcid.org/0000-0002-0957-7389
Sarah O John-OlabodeDepartment of Haematology & Blood Transfusion, College of Medicine, University of Lagos, Lagos, Nigeria.ORCID https://orcid.org/0000-0001-7130-9812
Adaiah P Soibi-HarryDepartment of Obstetrics & Gynaecology, Lagos University Teaching Hospital, Surulere, Lagos, Nigeria.ORCID https://orcid.org/0000-0001-5938-3235
Austin C OkoroDepartment of Obstetrics & Gynaecology, Lagos University Teaching Hospital, Surulere, Lagos, Nigeria.ORCID https://orcid.org/0000-0002-7175-3280
Adebola A AdejimiDepartment of Community Health & Primary Care, College of Medicine, University of Lagos, Lagos, Nigeria.ORCID https://orcid.org/0000-0003-3535-7344
Iyabo Y AdemuyiwaDepartment of Nursing Science, College of Medicine, University of Lagos, Lagos, Nigeria.ORCID https://orcid.org/0000-0002-8764-4380
Benedetto OsunwusiDepartment of Obstetrics & Gynaecology, Lagos University Teaching Hospital, Surulere, Lagos, Nigeria.ORCID https://orcid.org/0000-0002-0470-6153
Hameed AdelabuCenter for Clinical Trial, Research, & Implementation Science (CCTRIS), College of Medicine, University of Lagos, Lagos, Nigeria.
Omolola SalakoDepartment of Radiation Biology, Radiotherapy & Radiodiagnosis, College of Medicine, University of Lagos, Lagos, Nigeria.ORCID https://orcid.org/0000-0003-3165-8879

Funding

COMParative ASSessment of p16/Ki-67 DUal Staining Technology in women living with HIV (COMPASS-DUST study)K43TW011930 · FIC · COLLEGE OF MEDICINE, UNIVERSITY OF LAGOS · PI KEHINDE SHARAFADEEN OKUNADE · 2022 to 2026
$500k
FIC NIH HHS K43 TW011930
6 · The paper itself

Abstract

Purpose: This study investigated the prognostic performance of the systemic immune-inflammation index (SII) in patients with epithelial ovarian cancer (EOC) in Lagos, Nigeria. Methods: We performed a secondary analysis of the data of 91 women who had treatment for EOC between 2009 and 2018. The associations between pretreatment SII and survivals were tested. Results: Pretreatment SII more than 610.2 was a significant independent predictor of reduced progression-free survival (HR = 2.68; 95% CI, 1.17 to 6.09) while SII greater than 649.0 was a significant independent predictor of reduced 3-year overall survival (HR = 2.01; 95% CI, 1.01 to 3.99). Conclusion: These findings suggest that high SII may be a potential prognostic indicator and useful marker for more intensive surveillance and design of personalized treatment in patients with EOC.

Indexed as

AfricaEOCovarian canceroverall survivalprognosisprogression-free survivalSII

Identifiers

PMID37753357
PMCPMC10518822

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.