Evidence map›Paper›PMID 37753279›Full record

ArticleERJ open research2023

Laboratory and free-living gait performance in adults with COPD and healthy controls.

Joren Buekers, Dimitrios Megaritis, Sarah Koch, Lisa Alcock, Nadir Ammour, Clemens Becker, Stefano Bertuletti, Tecla Bonci, Philip Brown, Ellen Buckley and 26 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Gait differences between COPD and healthy controls: systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  2. Article
  3. Are Real-World Mobility Patterns Early Indicators of COPD Onset? Insights from Wrist-Worn Sensors.International journal of chronic obstructive pulmonary disease · 2026
    Article
  4. Digital assessment of real-world walking in people with impaired mobility: How many hours and days are needed?The international journal of behavioral nutrition and physical activity · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors at 20 institutions in 13 countries.

Joren BuekersISGlobal, Barcelona, Spain.ORCID https://orcid.org/0000-0003-4866-5741
Dimitrios MegaritisDepartment of Sport, Exercise and Rehabilitation, Northumbria University Newcastle, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0001-6786-4346
Sarah KochISGlobal, Barcelona, Spain.ORCID https://orcid.org/0000-0001-9461-8407
Lisa AlcockTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Nadir AmmourClinical Science and Operations, GlobalDevelopment, Sanofi R&D, Chilly-Mazarin, France.
Clemens BeckerRobert Bosch Gesellschaft für Medizinische Forschung, Stuttgart, Germany.
Stefano BertulettiDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.ORCID https://orcid.org/0000-0002-0450-9141
Tecla BonciDepartment of Mechanical Engineering and INSIGNEO Institute for In Silico Medicine, The University of Sheffield, Sheffield, UK.ORCID https://orcid.org/0000-0002-8255-4730
Philip BrownThe Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Ellen BuckleyDepartment of Mechanical Engineering and INSIGNEO Institute for In Silico Medicine, The University of Sheffield, Sheffield, UK.ORCID https://orcid.org/0000-0002-0968-6286
Sara C ButteryNational Lung and Heart Institute, Imperial College, London, UK.
Brian CaulfiedInsight Centre for Data Analytics, University College Dublin, Dublin, Ireland.
Andrea CereattiPolytechnic University of Torino, Department of Electronics and Telecommunications, Turin, Italy.
Nikolaos ChynkiamisDepartment of Sport, Exercise and Rehabilitation, Northumbria University Newcastle, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0002-9595-6974
Heleen DemeyerKU Leuven, Department of Rehabilitation Sciences and Pulmonary Rehabilitation, Respiratory Division, University Hospital Gasthuisberg, Leuven, Belgium.
Carlos EchevarriaTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Anja FreiEpidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-7134-1000
Clint HansenDepartment of Neurology, University Hospital Schleswig-Holstein and Kiel University, Kiel, Germany.
Jeffrey M HausdorffCenter for the Study of Movement, Cognition and Mobility, Neurological Institute, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Nicholas S HopkinsonNational Lung and Heart Institute, Imperial College, London, UK.ORCID https://orcid.org/0000-0003-3235-0454
Emily HumeDepartment of Sport, Exercise and Rehabilitation, Northumbria University Newcastle, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0003-0462-2395
Arne KuederleMachine Learning and Data Analytics Lab, Department of Artificial Intelligence in Biomedical Engineering, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Walter MaetzlerDepartment of Neurology, University Hospital Schleswig-Holstein and Kiel University, Kiel, Germany.ORCID https://orcid.org/0000-0002-5945-4694
Claudia MazzàDepartment of Mechanical Engineering and INSIGNEO Institute for In Silico Medicine, The University of Sheffield, Sheffield, UK.
Encarna M Micó-AmigoTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Arne MuellerNovartis Institutes for Biomedical Research, Basel, Switzerland.
Luca PalmeriniDepartment of Electrical, Electronic and Information Engineering "Guglielmo Marconi", University of Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0003-4758-662X
Francesca SalisDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.ORCID https://orcid.org/0000-0003-1380-6014
Kirsty ScottDepartment of Mechanical Engineering and INSIGNEO Institute for In Silico Medicine, The University of Sheffield, Sheffield, UK.
Thierry TroostersKU Leuven, Department of Rehabilitation Sciences and Pulmonary Rehabilitation, Respiratory Division, University Hospital Gasthuisberg, Leuven, Belgium.
Beatrix VereijkenDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.ORCID https://orcid.org/0000-0002-2231-8138
Henrik WatzPulmonary Research Institute at LungenClinic Grosshansdorf, Airway Research Center North, German Center for Lung Research (DZL), Grosshansdorf, Germany.
Lynn RochesterTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0001-5774-9272
Silvia Del DinTranslational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID https://orcid.org/0000-0003-1154-4751
Ioannis VogiatzisDepartment of Sport, Exercise and Rehabilitation, Northumbria University Newcastle, Newcastle upon Tyne, UK.
Judith Garcia-AymerichISGlobal, Barcelona, Spain.ORCID https://orcid.org/0000-0002-7097-4586
Newcastle upon Tyne Hospitals NHS Foundation Trust · GBInsigneo · GBUniversitat Pompeu Fabra · ESChristian-Albrechts-Universität zu Kiel · DEImperial College London · GBNational and Kapodistrian University of Athens · GRNorthumbria University · GBUniversity of Sassari · ITFriedrich-Alexander-Universität Erlangen-Nürnberg · DEGerman Center for Lung Research · DEGhent University Hospital · BEKU Leuven · BEMarconi University · ITNewcastle University · GBNorwegian University of Science and Technology · NONovartis (Switzerland) · CHPolitecnico di Torino · ITRobert Bosch Stiftung · DERush University Medical Center · USSanofi (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gait characteristics are important risk factors for falls, hospitalisations and mortality in older adults, but the impact of COPD on gait performance remains unclear. We aimed to identify differences in gait characteristics between adults with COPD and healthy age-matched controls during 1) laboratory tests that included complex movements and obstacles, 2) simulated daily-life activities (supervised) and 3) free-living daily-life activities (unsupervised). Methods: This case-control study used a multi-sensor wearable system (INDIP) to obtain seven gait characteristics for each walking bout performed by adults with mild-to-severe COPD (n=17; forced expiratory volume in 1 s 57±19% predicted) and controls (n=20) during laboratory tests, and during simulated and free-living daily-life activities. Gait characteristics were compared between adults with COPD and healthy controls for all walking bouts combined, and for shorter (≤30 s) and longer (>30 s) walking bouts separately. Results: Slower walking speed (-11 cm·s Conclusion: Gait impairment of adults with mild-to-severe COPD mainly manifests during relatively long walking bouts (>30 s) in free-living conditions. Future research should determine the underlying mechanism(s) of this impairment to facilitate the development of interventions that can improve free-living gait performance in adults with COPD.

Identifiers

PMID37753279
PMCPMC10518872
OpenAlexW4385948674

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.