Evidence map›Paper›PMID 37752529›Full record

ArticleBMC health services research2023

Implementing medication adherence interventions in four Dutch living labs; context matters.

Stijn Hogervorst, Marcia Vervloet, Ruby Janssen, Ellen Koster, Marcel C Adriaanse, Charlotte L Bekker, Bart J F van den Bemt, Marcel Bouvy, Eibert R Heerdink, Jacqueline G Hugtenburg and 4 more

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Article in BMC health services research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Stijn HogervorstDepartment of Health Sciences, Faculty of Science, Vrije Universiteit, Amsterdam, The Netherlands.
Marcia VervloetDepartment of Pharmaceutical Care, Nivel, Netherlands Institute for Health Services Research, Utrecht, The Netherlands. m.vervloet@nivel.nl.ORCID http://orcid.org/0000-0002-0325-9814
Ruby JanssenHogeschool Utrecht, Lectorate Innovations in Healthcare Processes in Pharmacology, Utrecht, The Netherlands.
Ellen KosterUtrecht Institute of Pharmaceutical Sciences, Divison of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, the Netherlands.
Marcel C AdriaanseDepartment of Health Sciences, Faculty of Science, Vrije Universiteit, Amsterdam, The Netherlands.
Charlotte L BekkerDepartment of Pharmacy, Radboud Institute for Health Sciences, Radboud University Medical Centre, Nijmegen, the Netherlands.
Bart J F van den BemtDepartment of Pharmacy, Radboud Institute for Health Sciences, Radboud University Medical Centre, Nijmegen, the Netherlands.
Marcel BouvyUtrecht Institute of Pharmaceutical Sciences, Divison of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, the Netherlands.
Eibert R HeerdinkUtrecht Institute of Pharmaceutical Sciences, Divison of Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, the Netherlands.
Jacqueline G HugtenburgAmsterdam Public Health Research Institute, Amsterdam UMC, Location VUMC, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.
Menno van WoerkomDutch Institute for Rational Use of Medicine (IVM), Utrecht, the Netherlands.
Hanneke ZwikkerDutch Institute for Rational Use of Medicine (IVM), Utrecht, the Netherlands.
Caroline van de Steeg-van GompelSIR Institute for Pharmacy Practice and Policy, Leiden, The Netherlands.
Liset van DijkDepartment of Pharmaceutical Care, Nivel, Netherlands Institute for Health Services Research, Utrecht, The Netherlands.

Funding

ZonMw 80-84800-98-24002
6 · The paper itself

Abstract

backgroundDespite the abundant availability of effective medication adherence interventions, uptake of these interventions into routine care often lacks. Examples of effective medication adherence interventions include telephone counseling, consult preparation and the teach-back method. Assessing context is an important step in understanding implementation success of interventions, but context is often not reported or only moderately described. This study aims to describe context-specific characteristics in four living labs prior to the implementation of evidence-based interventions aiming to improve medication adherence.

methodsA qualitative study was conducted within four living labs using individual interviews (n = 12) and focus groups (n = 4) with project leaders and involved healthcare providers. The four living labs are multidisciplinary collaboratives that are early adopters of medication adherence interventions in the Dutch primary care system. Context is defined as the environment or setting in which the proposed change is to be implemented. Interview topics to assess context were formulated based on the 'inner setting' and 'outer setting' domains of the Consolidated Framework for Implementation Research (CFIR). Interviews were recorded and transcribed verbatim. Transcripts were deductively analyzed.

resultsA total of 39 community pharmacists, pharmacy technicians, general practitioners and a home care employee participated in the (focus group) interviews. All four living labs proved to be pharmacy-driven and characterized by a high regard for innovation by staff members, a positive implementation climate, high levels of leadership engagement and high compatibility between the living labs and the interventions. Two living labs were larger in size and characterized by more formal communication. Two living labs were characterized by higher levels of cosmopolitanism which resulted in more adaptable interventions. Worries about external policy, most notably lack of reimbursement for sustainment and upscaling of the interventions, were shared among all living labs.

conclusionsContextual characteristics of four living labs that are early adopters of medication adherence interventions provide detailed examples of a positive implementation setting. These can be used to inform dissemination of medication adherence interventions in settings less experienced in implementing medication adherence interventions.

Indexed as

AltruismGeneral PractitionersCommunicationEthnicityHumansMedication AdherenceConsolidated framework for implementation research (CFIR)ContextImplementationInnovationLiving labsMedication adherencePharmaceutical careReal-world setting

Identifiers

PMID37752529
PMCPMC10523767

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.