Evidence map›Paper›PMID 37752344›Full record

ArticleEJNMMI research2023

Assessment of resting myocardial blood flow in regions of known transmural scar to confirm accuracy and precision of 3D cardiac positron emission tomography.

Robert M Bober, Richard V Milani, Sergey M Kachur, Daniel P Morin

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in EJNMMI research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05286593 (Quantification of Myocardial Blood Flow by 3D Positron Emission Tomography With High and Low Rate Rb82 Infusion Profiles), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05286593 phase4completednot on this map

Quantification of Myocardial Blood Flow by 3D Positron Emission Tomography With High and Low Rate Rb82 Infusion Profiles

TypeinterventionalSponsorOchsner Health SystemRan2021 to 2022Enrolled98ConditionsNormal Healthy Volunteers Without Chronic Medical Conditions, Coronary Artery Disease, Cardiac Risk Factors, Myocardial InfarctionArmsSlow Infusion of Rubidium-82
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Hybrid quantification of absolute perfusion requires accurate measurement of myocardial mass.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Robert M BoberDepartment of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Health, 1514 Jefferson Highway, New Orleans, LA, 70121-2483, USA. rbober@ochsner.org.ORCID http://orcid.org/0000-0003-4706-4442
Richard V MilaniDepartment of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Health, 1514 Jefferson Highway, New Orleans, LA, 70121-2483, USA.
Sergey M KachurDepartment of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Health, 1514 Jefferson Highway, New Orleans, LA, 70121-2483, USA.
Daniel P MorinDepartment of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Health, 1514 Jefferson Highway, New Orleans, LA, 70121-2483, USA.
Ochsner Health System · US

Funding

Bracco Diagnostics IIS-US-0147
6 · The paper itself

Abstract

backgroundComposite invasive and non-invasive data consistently demonstrate that resting myocardial blood flow (rMBF) in regions of known transmural myocardial scar (TMS) converge on a value of ~ 0.30 mL/min/g or lower. This value has been confirmed using the 3 most common myocardial perfusion agents (

resultsMedian rMBF (in mL/min/g) and COV in regions of TMS were 0.71 [IQR 0.52-1.02] and 0.16 with 4DM; 0.41 [0.34-0.54] and 0.10 with 4DM-FVD; 0.66 [0.51-0.85] and 0.11 with Cedars; 0.51 [0.43-0.61] and 0.08 with Emory-Votaw; 0.37 [0.30-0.42], 0.07 with Emory-Ottawa, and 0.26 [0.23-0.32], COV 0.07 with HeartSee.

conclusionsSWPs varied widely in low end accuracy based on measurement of rMBF in regions of known TMS. 3D PET using

trial registrationclinicaltrial.gov, NCT05286593, Registered December 28, 2021, https://clinicaltrials.gov/ct2/show/NCT05286593 .

Indexed as

Myocardial scarPositron emission tomography (PET)Resting myocardial blood flow

Identifiers

PMID37752344
PMCPMC10522549
OpenAlexW4387077270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.