Evidence map›Paper›PMID 37752251›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Treatment strategy in laryngeal chondrosarcoma: a multicenter study of 43 cases.

Marianne Schleich, Laurent Laccourreye, Remi Marianowski, Xavier Dufour, Emmanuel Babin, Vianney Bastit, Jean Paul Marie, Cécile Badoual, Pierre Philouze, Florent Espitalier and 2 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Regional and distant metastases from laryngeal chondrosarcoma: a systematic review.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026
    Pooled it
  2. Crico-tracheal resection and anastomosis for primary and secondary tumours of the laryngo-tracheal junction: a single centre series of 78 patients.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marianne SchleichDepartment of Otolaryngology-Head and Neck Surgery, University Hospital of Tours, 2 Boulevard Tonnellé, 37000, Tours, France. marianne.schleich@hotmail.fr.ORCID http://orcid.org/0000-0002-0435-3642
Laurent LaccourreyeDepartment of Otolaryngology-Head and Neck Surgery, University Hospital of Angers, Angers, France.
Remi MarianowskiDepartment of Otolaryngology-Head and Neck Surgery, University Hospital of Brest, Brest, France.
Xavier DufourDepartment of Otolaryngology-Head and Neck Surgery, University Hospital of Poitiers, Poitiers, France.
Emmanuel BabinDepartment of Otolaryngology-Head and Neck Surgery, University Hospital of Caen, Caen, France.
Vianney BastitDepartment of Otolaryngology-Head and Neck Surgery, François Baclesse Center, Caen, France.
Jean Paul MarieDepartment of Otolaryngology-Head and Neck Surgery, University Hospital of Rouen, Rouen, France.
Cécile BadoualDepartment of Pathology, European Hospital of Georges Pompidou, Paris, France.
Pierre PhilouzeDepartment of Otolaryngology-Head and Neck Surgery, Croix Rousse University Hospital, Lyons, France.
Florent EspitalierDepartment of Otolaryngology-Head and Neck Surgery, University Hospital of Nantes, Nantes, France.
Gonzague Du Bouexic De PinieuxDepartment of Pathology, University Hospital of Tours, Tours, France.
Sylvain MoriniereDepartment of Otolaryngology-Head and Neck Surgery, University Hospital of Tours, 2 Boulevard Tonnellé, 37000, Tours, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLaryngeal chondrosarcoma is a rare tumor that mostly affects the cricoid cartilage. The aim of this study was to compare outcomes between the various treatments of this pathology as there are no official guidelines for this pathology.

methodsA retrospective analysis of the pathology database of nine French tertiary care centers was conducted. Outcomes of patients treated by total laryngectomy were compared with those treated by more conservative approaches (endoscopic debulking, median thyrotomy, partial laryngectomy). Two Kaplan-Meier survival analyses were performed: one to assess the overall survival rate and the other to assess laryngeal preservation over time.

resultsA total of 43 patients were enrolled: 12 with total laryngectomy as the initial treatment, and 31 who initially underwent laryngeal-preserving treatment. With conservative treatment, laryngeal function was preserved in 96% and 75% of patients at 1 and 5 years, respectively. Conservative treatment did not reduce the overall survival rate.

conclusionThese results suggest that laryngeal preservation should be considered as the initial treatment in cases of laryngeal chondrosarcoma.

Indexed as

Bone NeoplasmsChondrosarcomaLaryngeal NeoplasmsLarynxHumansLaryngectomyRetrospective StudiesTreatment OutcomeChondrosarcomaLaryngeal cancerLaryngeal tumorLaryngectomyLarynx

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.