Evidence map›Paper›PMID 37751988›Full record

SynthesisBMJ open respiratory research2023

Aetiological agents of adult community-acquired pneumonia in Japan: systematic review and meta-analysis of published data.

Yuji Fujikura, Kohei Somekawa, Toshie Manabe, Nobuyuki Horita, Hiroshi Takahashi, Futoshi Higa, Kazuhiro Yatera, Naoyuki Miyashita, Yoshifumi Imamura, Naoki Iwanaga and 2 more

Open access · goldAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMJ open respiratory research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Reply to Mitaka et al.Open forum infectious diseases · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Antibiotic therapy for bacterial pneumonia.Journal of pharmaceutical health care and sciences · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 1 country.

Yuji FujikuraDivision of Infectious Diseases and Respiratory Medicine, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan fujikura@ndmc.ac.jp.ORCID 0000-0002-7384-2167
Kohei SomekawaDepartment of Pulmonology, Yokohama City University Graduate School of Medicine, Yokohama, Kanagawa, Japan.
Toshie ManabeGraduate School of Medical Science, Nagoya City University, Nagoya, Aichi, Japan.
Nobuyuki HoritaChemotherapy Center, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.
Hiroshi TakahashiDepartment of Respiratory Medicine, Saka General Hospital, Shiogama, Miyagi, Japan.
Futoshi HigaDivision of Respiratory Medicine, National Hospital Organization Okinawa National Hospital, Ginowan, Okinawa, Japan.
Kazuhiro YateraDepartment of Respiratory Medicine, University of Occupational and Environmental Health, Japan, Kitakyushu, Fukuoka, Japan.ORCID 0000-0002-2955-4432
Naoyuki MiyashitaFirst Department of Internal Medicine, Division of Respiratory Medicine, Infectious Disease and Allergology, Kansai Medical University, Hirakata, Osaka, Japan.
Yoshifumi ImamuraMedical Education Development Center, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan.
Naoki IwanagaDepartment of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan.
Hiroshi MukaeDepartment of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Nagasaki, Japan.
Akihiko KawanaDivision of Infectious Diseases and Respiratory Medicine, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
Nagasaki University Hospital · JPKansai Medical University · JPNagasaki University · JPNagoya City University · JPNational Defense Medical College · JPNational Defense Medical College Hospital · JPNational Hospital Organization · JPUniversity of Occupational and Environmental Health Japan · JPYokohama City University · JPYokohama City University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEpidemiological information is essential in providing appropriate empiric antimicrobial therapy for pneumonia. This study aimed to clarify the epidemiology of community-acquired pneumonia (CAP) by conducting a systematic review of published studies in Japan.

designSystematic review. DATA SOURCE: PubMed and Ichushi web database (January 1970 to October 2022). ELIGIBILITY CRITERIA: Clinical studies describing pathogenic micro-organisms in CAP written in English or Japanese, excluding studies on pneumonia other than adult CAP, investigations limited to specific pathogens and case reports. DATA EXTRACTION AND SYNTHESIS: Patient setting (inpatient vs outpatient), number of patients, concordance with the CAP guidelines, diagnostic criteria and methods for diagnosing pneumonia pathogens as well as the numbers of each isolate. A meta-analysis of various situations was performed to measure the frequency of each aetiological agent.

resultsFifty-six studies were included and 17 095 cases of CAP were identified. Pathogens were undetectable in 44.1% (95% CI 39.7% to 48.5%).

conclusionThe epidemiology of CAP varies depending on the situation, such as in the hospital versus outpatient setting. Viruses are more frequently detected by exhaustive genetic searches, resulting in a significant variation in epidemiology.

Indexed as

Community-Acquired InfectionsPneumoniaPneumonia, BacterialAdultCommunity-Acquired PneumoniaHaemophilus influenzaeHospitalizationHumansJapanStreptococcus pneumoniaebacterial infectionpneumoniarespiratory infectionviral infection

Identifiers

PMID37751988
PMCPMC10533802
OpenAlexW4387063707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.