Evidence map›Paper›PMID 37751547›Full record

ArticleACS chemical neuroscience2023

Identifying and Measuring Endogenous Peptides through Peptidomics.

James W Checco

Open access · greenAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Neuropeptidomics of the American LobsterJournal of proteome research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

James W CheccoDepartment of Chemistry, University of Nebraska─Lincoln, Lincoln, Nebraska 68588, United States.ORCID 0000-0003-1165-6163
University of Nebraska–Lincoln · US

Funding

Chemical approaches to interrogate neuropeptide and peptide hormone signaling in diseaseR35GM142784 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI James William Checco · 2021 to 2026
$2.5M
NIGMS NIH HHS R35 GM142784
6 · The paper itself

Abstract

Endogenous peptides, such as neuropeptides and peptide hormones, play important roles in intercellular communication, can provide information on physiology, and are potential sources of biomarkers. Mass spectrometry-based peptidomics methods are underutilized tools to identify and measure endogenous peptides in a relatively nontargeted manner. The purpose of this Viewpoint is to serve as a brief introduction to the field of peptidomics so that researchers interested in studying endogenous peptides are aware of this powerful approach and can consider its application.

Indexed as

NeuropeptidesPeptide HormonesBiomarkersMass SpectrometryProteomicsBiomarkersNeuropeptidesPeptide Hormonesmass spectrometryNeuropeptidespeptide hormonespeptidomics

Identifiers

PMID37751547
PMCPMC10614431
OpenAlexW4387040483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.