Evidence map›Paper›PMID 37751138›Full record

ArticleAdvances in experimental medicine and biology2023

KDM5 Lysine Demethylases in Pathogenesis, from Basic Science Discovery to the Clinic.

Shang-Min Zhang, Jian Cao, Qin Yan

Abstract read
PubMed Publisher
In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. X and Y Differences in Melanoma Survival Between the Sexes.Pigment cell & melanoma research · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Shang-Min ZhangSchool of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China. zhangshm@shanghaitech.edu.cn.
Jian CaoRutgers Cancer Institute of New Jersey, New Brunswick, NJ, 08901, USA. jian.cao@rutgers.edu.
Qin YanDepartment of Pathology, Yale Cancer Center, Yale Stem Cell Center, Yale Center for Immuno-Oncology, Yale Center for Research on Aging, Yale School of Medicine, P.O. Box 208023, New Haven, CT, 06520-8023, USA. qin.yan@yale.edu.
Rutgers, The State University of New Jersey · USShanghaiTech University · CNYale Cancer Center · US

Funding

TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Tracie Saunders · 1997 to 2026
$94.5M
Yale SPORE in Skin CancerP50CA121974 · NCI · YALE UNIVERSITY · PI MARCUS W BOSENBERG, Harriet M. Kluger · 2006 to 2026
$43.9M
Hepatitis B virus integrations in KMT2B drive hepatocellular carcinomaR01CA272578 · NCI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI Jian Cao · 2022 to 2026
$2.2M
TARGETING HISTONE DEMETHYLASE KDM5B IN BREAST CANCERR01CA237586 · NCI · YALE UNIVERSITY · PI YAN, QIN · 2019 to 2023
$1.9M
NCI NIH HHS P30 CA072720NCI NIH HHS P50 CA121974NCI NIH HHS R01 CA237586
6 · The paper itself

Abstract

The histone lysine demethylase 5 (KDM5) family proteins are Fe

Indexed as

Ambulatory Care FacilitiesLysineCatalytic DomainCell DifferentiationChromatinChromatinLysineAntitumor immunityCancerDrug resistanceHistone demethylaseJumonjiKDM5Stem cell

Identifiers

PMID37751138
OpenAlexW4387033122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.