Evidence map›Paper›PMID 37751106›Full record

ArticleApoptosis : an international journal on programmed cell death2024

Involvement of CD44 and MAPK14-mediated ferroptosis in hemorrhagic shock.

Haoran Ye, Shasha He, Yuan Du, Yuchen Wang, Yahui Hu, Chunxia Zhao, Yueting Jin, Fangyu Liu, Yuhong Guo

Abstract read
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In one paragraph

Article in Apoptosis : an international journal on programmed cell death, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Computational discovery ofFrontiers in immunology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Haoran Ye *Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Shasha He *Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yuan DuBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yuchen WangBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yahui HuTianjin University of Traditional Chinese Medicine, Tianjin, China.
Chunxia ZhaoBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yueting JinBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Fangyu LiuBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Yuhong GuoBeijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China. docgyh2022@163.com.
Beijing Hospital of Traditional Chinese Medicine · CNBeijing University of Chinese Medicine · CNCapital Medical University · CNTianjin University of Traditional Chinese Medicine · CN

Funding

National Natural Science Foundation of China 82274283
6 · The paper itself

Abstract

To elucidate the induction of ferroptotic pathways and the transcriptional modulation of pivotal genes in the context of hemorrhagic shock. The R software was used to analyze the GSE64711 dataset, isolating genes relevant to ferroptosis. Enrichment analyses and protein interaction networks were assembled. Using WGCNA hub genes were identified and intersected with ferroptosis-related genes, highlighting hub genes CD44 and MAPK14. In a rat hemorrhagic shock model, cardiac ROS, Fe

Indexed as

FerroptosisMitogen-Activated Protein Kinase 14Shock, HemorrhagicAnimalsApoptosisRatsReactive Oxygen SpeciesMitogen-Activated Protein Kinase 14Reactive Oxygen SpeciesBioinformaticsCD44FerroptosisGene expression omnibus databaseHemorrhagic shockMAPK14

Identifiers

PMID37751106
OpenAlexW4387032940

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.