ArticleJournal of autism and developmental disorders2025
Consanguinity as a Risk Factor for Autism.
Article in Journal of autism and developmental disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Association between consanguinity and neurological and developmental disorders in pediatric patients: A retrospective cohort study in Jazan, Saudi Arabia.World journal of clinical pediatrics · 2026Article
- Risk Factors for Autism Spectrum Disorder in the Middle East and North Africa Region: A Systematic Review and Meta-Analysis of Confounder-Adjusted Studies.Journal of autism and developmental disorders · 2026Article
- Exploring the Association Between Parental Age and Autism Spectrum Disorder Risk in Qatar.Journal of autism and developmental disorders · 2026Article
- Mothers' knowledge and home care practices for children with autism spectrum disorder in Diwaniyah, Iraq.Frontiers in child and adolescent psychiatry · 2026Article
- Uncovering the Molecular Signatures of Rare Genetic Diseases in the Punjabi Population.International journal of molecular sciences · 2025Observational
- Genetic Association and Functional Prediction of PTEN and TSC1 3'UTR Variants in Autism Spectrum Disorder Among Tunisian Patients.Molecular neurobiology · 2025Article
- Autism spectrum disorder in Saudi Arabia: Clinical dynamics from a multi-center study.Saudi medical journal · 2025Article
- Genetic and Environmental Risk Factors for Autism Spectrum Disorder in Saudi Arabia: A Systematic Review.Cureus · 2025Review
- Recessive genetic contribution to congenital heart disease in 5,424 probands.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Maternal attitudes and home-based interventions for enhancing social, attention, and language skills in children with autism in Diwaniyah, Iraq.Frontiers in psychiatry · 2025Article
- Consanguinity:Sultan Qaboos University medical journal · 2025Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
purposeGenetic and environmental risk factors associated with Autism Spectrum Disorders (ASD) continue to be a focus of research worldwide. Consanguinity, the cultural practice of marrying within a family, is common in cultures and societies of the Middle East, North Africa and parts of Asia. Consanguinity has been investigated as a risk factor for ASD in a limited number of studies, with mixed results. We employed registry and survey data from Qatar to evaluate the role of consanguinity as a risk factor for ASD.
methodsData were sourced from a national registry and a population-based survey of autism recently conducted in Qatar. We selected a sample of 891 children (mean age: 8.3 years) with (N = 361) or without (N = 530) ASD. Data on consanguinity and covariates were collected through questionnaires and interviews.
resultsThe prevalence of consanguinity in the overall sample was 41.2% with no significant difference between cases and controls (42.1% vs 41.3%; p = .836). In adjusted multiple logistic regression analyses, consanguinity was not associated with risk of ASD (aOR = 1.065; 95% CI: .751-1.509; NS).
conclusionParental consanguinity was not associated with autism risk in our study. Replication in other populations with high rates of consanguineous unions is recommended.
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