Evidence map›Paper›PMID 37751097›Full record

ArticleJournal of autism and developmental disorders2024

Machine Learning Differentiation of Autism Spectrum Sub-Classifications.

R Thapa, A Garikipati, M Ciobanu, N P Singh, E Browning, J DeCurzio, G Barnes, F A Dinenno, Q Mao, R Das

Abstract read
In one paragraph

Article in Journal of autism and developmental disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

R ThapaMontera, Inc dba Forta, 548 Market St, PMB 89605, San Francisco, CA, USA.
A GarikipatiMontera, Inc dba Forta, 548 Market St, PMB 89605, San Francisco, CA, USA.
M CiobanuMontera, Inc dba Forta, 548 Market St, PMB 89605, San Francisco, CA, USA.
N P SinghMontera, Inc dba Forta, 548 Market St, PMB 89605, San Francisco, CA, USA.
E BrowningMontera, Inc dba Forta, 548 Market St, PMB 89605, San Francisco, CA, USA.
J DeCurzioMontera, Inc dba Forta, 548 Market St, PMB 89605, San Francisco, CA, USA.
G BarnesMontera, Inc dba Forta, 548 Market St, PMB 89605, San Francisco, CA, USA.
F A DinennoMontera, Inc dba Forta, 548 Market St, PMB 89605, San Francisco, CA, USA.
Q MaoMontera, Inc dba Forta, 548 Market St, PMB 89605, San Francisco, CA, USA. qmao@fortahealth.com.ORCID http://orcid.org/0000-0001-6001-6723
R DasMontera, Inc dba Forta, 548 Market St, PMB 89605, San Francisco, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeDisorders on the autism spectrum have characteristics that can manifest as difficulties with communication, executive functioning, daily living, and more. These challenges can be mitigated with early identification. However, diagnostic criteria has changed from DSM-IV to DSM-5, which can make diagnosing a disorder on the autism spectrum complex. We evaluated machine learning to classify individuals as having one of three disorders of the autism spectrum under DSM-IV, or as non-spectrum.

methodsWe employed machine learning to analyze retrospective data from 38,560 individuals. Inputs encompassed clinical, demographic, and assessment data.

resultsThe algorithm achieved AUROCs ranging from 0.863 to 0.980. The model correctly classified 80.5% individuals; 12.6% of individuals from this dataset were misclassified with another disorder on the autism spectrum.

conclusionMachine learning can classify individuals as having a disorder on the autism spectrum or as non-spectrum using minimal data inputs.

Indexed as

Autism Spectrum DisorderMachine LearningAdolescentAdultAlgorithmsChildChild, PreschoolDiagnostic and Statistical Manual of Mental DisordersFemaleHumansMaleRetrospective StudiesYoung AdultAutismClassificationDiagnosticsMachine learning

Identifiers

PMID37751097
PMCPMC11461775

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.