Evidence map›Paper›PMID 37750958›Full record

ArticleWorld journal of urology2023

Intrarenal pressure study using 7.5 French flexible ureteroscope with or without ureteral access sheath in an ex-vivo porcine kidney model.

Zhenyuan Han, Baosen Wang, Xiaohui Liu, Tao Jing, WenSu Yue, Yuliang Wang, Dong Wang

Abstract read
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In one paragraph

Article in World journal of urology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Zhenyuan Han *Department of Urology, The People's Hospital of Huantai, Zibo, Shandong, China.
Baosen Wang *Department of Urology, The People's Hospital of Huantai, Zibo, Shandong, China.
Xiaohui LiuDepartment of Urology, The People's Hospital of Huantai, Zibo, Shandong, China.
Tao JingDepartment of Urology, The People's Hospital of Huantai, Zibo, Shandong, China.
WenSu YueDepartment of Urology, The People's Hospital of Huantai, Zibo, Shandong, China.
Yuliang WangDepartment of Urology, The People's Hospital of Huantai, Zibo, Shandong, China.
Dong WangDepartment of Urology, The People's Hospital of Huantai, Zibo, Shandong, China. dr.dongwang@foxmail.com.
Xintai People's Hospital · CNThe Fourth People's Hospital of Zibo City · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction7.5F digital fURS and 9.5/11.5F ureteral access sheaths (UAS), both conventional (cUAS) and vacuum-assisted (vaUAS), are commercially available. Irrigation increases intrarenal pressure (IRP). This study analyzes the IRP with various irrigation rates using 7.5F fURS without UAS or with either cUAS or vaUAS in an ex-vivo porcine model. Pyelo-tubular backflow was also studied during these experiments. MATERIALS AND

methods11 porcine kidneys were used. 7.5F digital fURS was tested without UAS and with 9.5/11.5F cUAS and vaUAS. 6F pressure monitor catheters were placed into the upper and lower calyces. IRPs were recorded under different irrigation rates. When vaUAS was used, the air vent was either open or closed. 300 mmHg aspiration pressure was chosen. Lastly, contrasted irrigation fluid was delivered until IRP reached above 30 mmHg. Fluoroscopy images were obtained at 5 mmHg intervals over this threshold to study the pyelo-tubular backflow.

resultsUsing cUAS, IRP reached 30 mmHg with irrigation rates between 60 and 70 cc/min. Using vaUAS with vent closed, IRP never exceeded 10 mmHg with irrigation up to 120 cc/min. vaUAS with vent open performed marginally better than cUAS. fURS without UAS performed better than cUAS. Pyelo-tubular backflow became prominent at 40 mmHg.

conclusionIn an ex-vivo porcine model, 7.5F fURS could be used safely without UAS with irrigation rates up to 120 cc/min. The safety margin dropped to 60-70 cc/min with cUAS. vaUAS with vent closed maintained IRP < 10 mmHg with irrigation rates up to 120 cc/min. Pyelo-tubular backflow was observed with IRP > 35 mmHg.

Indexed as

Kidney CalculiUreterAnimalsKidneyPressureSwineTherapeutic IrrigationUreteroscopesUreteroscopyEx-vivo porcine modelFlexible ureteroscopyIntrarenal pressureUreteral access sheath

Identifiers

PMID37750958
OpenAlexW4387033271

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.