Evidence map›Paper›PMID 37750685›Full record

ArticleMicrobiology spectrum2023

Interactive effects between

Yu P Song, Man F Tang, Agnes S Y Leung, Kin P Tao, Oi M Chan, Gary W K Wong, Paul K S Chan, Renee W Y Chan, Ting F Leung

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Yu P SongDepartment of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong, China.
Man F TangDepartment of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong, China.
Agnes S Y LeungDepartment of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong, China.
Kin P TaoDepartment of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong, China.
Oi M ChanDepartment of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong, China.
Gary W K WongDepartment of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong, China.
Paul K S ChanDepartment of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong, China.ORCID 0000-0002-6360-4608
Renee W Y ChanDepartment of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong, China.ORCID 0000-0001-6485-0926
Ting F LeungDepartment of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong, China.ORCID 0000-0002-6469-1926
Chinese University of Hong Kong · HK

Funding

Chinese University of Hong Kong (CUHK) Direct Grant 2021.052Hong Kong Institute of Allergy N/A
6 · The paper itself

Abstract

importanceThis case-control study investigated the interaction between CDHR3 genotypes and rhinovirus (RV) species on disease severity in Hong Kong children hospitalized for respiratory tract infection (RTI). There were synergistic effects between RV-C and CDHR3 SNPs for RTI severity, which was mainly driven by RV-C. Specifically, rs6967330 and rs140154310 alone and their epistatic interaction were associated with RV-C-related and severe RTIs in our subjects. Therefore, genotyping of CDHR3 SNPs may help physicians formulate prediction models for severity of RV-associated RTIs.

Indexed as

CDHR3childrengene-environment interactionrespiratory tract infectionrhinoviruswheezing

Identifiers

PMID37750685
PMCPMC10581227
OpenAlexW4387033544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.