Evidence map›Paper›PMID 37750563›Full record

ReviewJournal of the American Heart Association2023

Pickering Syndrome: An Overlooked Renovascular Cause of Recurrent Heart Failure.

Viola Sanga, Eleonora Bertoli, Filippo Crimì, Giulio Barbiero, Michele Battistel, Teresa Maria Seccia, Gian Paolo Rossi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of the American Heart Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Management of Renovascular Hypertension and Renal Denervation in Patients with Hypertension: An Italian Nationwide Survey.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Viola SangaHypertension and Emergency Unit, Department of Medicine University of Padua Padua Italy.ORCID 0000-0003-4735-1636
Eleonora BertoliHypertension and Emergency Unit, Department of Medicine University of Padua Padua Italy.ORCID 0000-0002-8258-9052
Filippo CrimìHypertension and Emergency Unit, Department of Medicine University of Padua Padua Italy.ORCID 0000-0001-6822-1430
Giulio BarbieroInstitute of Radiology, Department of Medicine University of Padua Padua Italy.ORCID 0000-0002-1157-3635
Michele BattistelInstitute of Radiology, Department of Medicine University of Padua Padua Italy.
Teresa Maria SecciaHypertension and Emergency Unit, Department of Medicine University of Padua Padua Italy.ORCID 0000-0002-3639-4086
Gian Paolo RossiHypertension and Emergency Unit, Department of Medicine University of Padua Padua Italy.ORCID 0000-0002-7963-0931
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ABSTRACTRecurring and rapidly developing (flash) pulmonary edema is the hallmark of Pickering syndrome, affecting patients with hypertension and atherosclerotic renal artery stenosis (either bilateral or unilateral) in a solitary functioning kidney, and impaired renal function. We herein report on a series of consecutive patients with recurrent hospital admissions for pulmonary edema, impaired renal function (chronic kidney disease class 4-5), and atherosclerotic bilateral renal artery stenosis, in whom Pickering syndrome had been long neglected. We also describe a streamlined diagnostic strategy entailing little or no need for contrast medium, thus carrying no risks of further worsening of renal function. This allowed us to make the correct diagnosis and opened the way to revascularization by percutaneous transluminal renal angioplasty with stent, which provided swift recovery of kidney function with resolution of pulmonary congestion and long-term pulmonary edema- and dialysis-free survival in all cases. In summary, these findings support the following key messages: (1) considering the diagnosis of Pickering syndrome, followed by searching atherosclerotic renal artery stenosis, is an essential step toward a life-saving revascularization that avoids dialysis and an otherwise poor outcome; and (2) a simplified strategy entailing little or no need for contrast medium, carrying no associated risks of deteriorating renal function, permits the diagnosis of Pickering syndrome.

Indexed as

AtherosclerosisHeart FailurePulmonary EdemaRenal Artery ObstructionAngioplastyHumansRenal ArteryStentsSyndromeatherosclerosischronic kidney diseasepulmonary edemarenal artery stenosisrevascularization, angioplasty, stenting

Identifiers

PMID37750563
PMCPMC10727269
OpenAlexW4387034108

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.