Evidence map›Paper›PMID 37750387›Full record

ArticleHuman vaccines & immunotherapeutics2023

Do adolescents need a rubella vaccination campaign? Rubella serosurvey among healthy children in Hangzhou, China.

Xiaozhen Wang, Yuyang Xu, Xuechao Zhang, Xiaoping Zhang, Jian Du, Xinren Che, Wenwen Gu, Jun Wang, Wei Jiang, Yan Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human vaccines & immunotherapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xiaozhen WangSchool of Public Health, Hangzhou Normal University, Hangzhou, China.
Yuyang XuDepartment of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou, China.
Xuechao ZhangDepartment of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou, China.
Xiaoping ZhangDepartment of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou, China.
Jian DuDepartment of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou, China.
Xinren CheDepartment of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou, China.
Wenwen GuDepartment of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou, China.
Jun WangDepartment of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou, China.ORCID 0000-0001-6165-6220
Wei JiangDepartment of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou, China.
Yan LiuDepartment of Expanded Program on Immunization, Hangzhou Center for Disease Control and Prevention, Hangzhou, China.ORCID 0000-0002-7894-121X
Hangzhou Center for Disease Control and Prevention · CNHangzhou Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the seroprevalence of rubella antibodies and factors associated with antibody seropositivity after vaccination among healthy children aged 14 and below. A multi-stage stratified random sampling method was employed to recruit participants for the rubella serological test. An enzyme-linked immunosorbent assay method was used to detect human IgG antibodies with avidity for rubella virus in the sera of participants. Univariate and multivariate analyses were used to analyze associations between variables. A total of 778 subjects were included in the subsequent analysis. The overall positive rate of rubella antibody was 83.0% (95%CI: 80.2-85.5%), and the overall geometric mean concentration (GMC) was 58.05 IU/ml. In multivariate analysis, gender, residence, birth year group, and time since the last rubella-containing vaccines (RCV) vaccination were significantly associated with the seroprevalence of rubella antibodies. Our study showed a decreasing trend in rubella antibody positivity and GMC in the population aged five to 14 years. Therefore, we recommend a catch-up dose of RCV for adolescents and young people aged over 14 years not yet vaccinated.

Indexed as

MeaslesRubellaAdolescentAntibodies, ViralChildChinaHumansImmunization ProgramsMeasles-Mumps-Rubella VaccineRubella VaccineSeroepidemiologic StudiesVaccinationAntibodies, ViralMeasles-Mumps-Rubella VaccineRubella VaccinechildreninfantRubellarubella antibodiesrubella vaccine

Identifiers

PMID37750387
PMCPMC10524778
OpenAlexW4387033876

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.