ArticleClinical ophthalmology (Auckland, N.Z.)2023
Incidence and Management of Epithelial-Related Complications After SMILE.
Article in Clinical ophthalmology (Auckland, N.Z.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- Management of Severe Epithelial Ingrowth Following KLEx Using Crocodile-Forceps Extraction: Surgical Technique and Literature Review.Journal of clinical medicine · 2026Review
- Intraoperative Safety and Postoperative Complications After SMILE Pro: A Retrospective Case Series of 916 Eyes.Journal of clinical medicine · 2026Article
- Comparison of four different techniques for lenticule dissection in small incision lenticule extraction.International journal of ophthalmology · 2026Article
- Effects of age and sex on the early visual outcomes of small-incision lenticule extraction for myopia correction.BMC ophthalmology · 2025Article
- Visual outcomes for the initial 500 eyes treated with keratorefractive lenticule extraction (KLEx) for myopia and myopic astigmatism at a single-site.Medical hypothesis, discovery & innovation ophthalmology journal · 2025Article
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To investigate the incidence and management of only epithelial-related complications following small incision lenticule extraction (SMILE). Patients and Methods: A retrospective, single-site study analyzed patients who underwent SMILE at Hoopes Vision Clinic in Draper, Utah, from June 2017 to February 2023. Demographic data and preoperative parameters were reviewed. Postoperatively, patients were assessed for visual acuity and complications at different time points. Statistical analyses were conducted between the control and complication groups. Results: Four hundred and thirty-two eyes of 220 patients received SMILE. Postoperative epithelial-related complications were indicated in 68 (15.7%) eyes, including anterior basement membrane (ABM) changes (five [1.2%]) eyes), epithelial ingrowth (nine [2.1%] eyes), erosion (two [0.5%] eyes), rough epithelium (18 [4.2%] eyes), epithelial defect (12 [2.8%] eyes), diffuse lamellar keratitis (DLK) secondary to epitheliopathy (two [0.5%] eyes), microstriae secondary to epitheliopathy (four [0.9%] eyes), interface debris (21 [4.9%] eyes), and incisional fibrosis (one [0.2%] eye). There was a statistically significant difference in age, with older patients more likely to develop epitheliopathy postoperatively ( Conclusion: In our study, epithelial-related complications were more prevalent in older patients and predisposed patients to require PRK enhancements after recovery from SMILE. Despite the incidence of epithelial-related complications, visual prognoses were favorable and achieved through various management strategies.
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