Evidence map›Paper›PMID 37750091›Full record

ReviewInternational journal of nanomedicine2023

Application of Single Extracellular Vesicle Analysis Techniques.

Junquan Zhu, Feifeng Wu, Cuifang Li, Jueyi Mao, Yang Wang, Xin Zhou, Haotian Xie, Chuan Wen

Open access · goldAbstract readReview
In one paragraph

Review in International journal of nanomedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
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  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Research on exosomes in cancer multidrug resistance and clinical translation.Extracellular vesicles and circulating nucleic acids · 2026
    Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Extracellular Vesicle Preparation and Analysis: A State-of-the-Art Review.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Junquan ZhuDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Feifeng Wu *Department of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Cuifang Li *Department of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Jueyi Mao *Department of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Yang Wang *Department of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Xin Zhou *Department of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Haotian Xie *Department of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.
Chuan WenDepartment of Pediatrics, The Second Xiangya Hospital, Central South University, Changsha, People's Republic of China.ORCID 0000-0001-6955-670X
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are lipid containers that are actively released by cells and contain complex molecular cargoes. These cargoes include abundant material such as genomes and proteins from cells of origin. They are involved in intercellular communication and various pathological processes, showing excellent potential for diagnosing and treating diseases. Given the significant heterogeneity of EVs in complex physiopathological processes, unveiling their composition is essential to understanding their function. Bulk detection methods have been previously used to analyze EVs, but they often mask their heterogeneity, leading to the loss of valuable information. To overcome this limitation, single extracellular vesicle (SEV) analysis techniques have been developed and advanced. These techniques allow for analyzing EVs' physical information and biometric molecules at the SEV level. This paper reviews recent advances in SEV detection methods and summarizes some clinical applications for SEV detection strategies.

Indexed as

Extracellular VesiclesCell Communicationdetection methodsdisease diagnosisheterogeneitynew therapiessingle extracellular vesicle analysis

Identifiers

PMID37750091
PMCPMC10518151
OpenAlexW4386897616

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.