Evidence map›Paper›PMID 37750016›Full record

ArticleEpidemiology and infection2023

Nosocomial outbreak in a respiratory ward caused by the SARS-CoV-2 Omicron BA 5.2.1 subvariant associated with non-severe illness in vaccinated patients.

Guduru Gopal Rao, Shamiso Jinjika, Dianne James, Nyarayi Mukombe, Bharat Patel, Amelie Chietcheu, Christine Macmanus, David Adeboyeku, Emma Davies, Benjamin Brown

Abstract read
In one paragraph

Article in Epidemiology and infection, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guduru Gopal RaoDepartments of Microbiology, Northwick Park Hospital, London, UK.ORCID 0000-0002-8108-4431
Shamiso JinjikaInfection Prevention and Control, Northwick Park Hospital, London, UK.
Dianne JamesInfection Prevention and Control, Northwick Park Hospital, London, UK.
Nyarayi MukombeInfection Prevention and Control, Northwick Park Hospital, London, UK.
Bharat PatelDepartments of Microbiology, Northwick Park Hospital, London, UK.
Amelie ChietcheuRespiratory Medicine, Northwick Park Hospital, London, UK.
Christine MacmanusRespiratory Medicine, Northwick Park Hospital, London, UK.
David AdeboyekuRespiratory Medicine, Northwick Park Hospital, London, UK.
Emma DaviesDepartment of Virology, Manchester University NHS Foundation Trust, Manchester, UK.
Benjamin BrownDepartment of Virology, Manchester University NHS Foundation Trust, Manchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this short report, we describe an outbreak of COVID-19 caused by Omicron subvariant BA.5.2.1 in highly vaccinated patients in a respiratory ward in a large acute general hospital in North West London, United Kingdom. The attack rate was high (14/33 (42%)) but the clinical impact was relatively non-severe including in patients who were at high risk of severe COVID-19. Twelve of fourteen patients had COVID-19 vaccinations. There was only one death due to COVID-19 pneumonitis. The findings of this outbreak investigation suggest that while the transmissibility of Omicron BA.5.2.1 subvariant is high, infections caused by this strain are non-severe in vaccinated patients, even if they are at high risk of severe COVID-19 infection.

Indexed as

COVID-19Cross InfectionDisease OutbreaksHospitals, GeneralHumansSARS-CoV-2COVID-19outbreaksvaccines

Identifiers

PMID37750016
PMCPMC10600893

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.