Evidence map›Paper›PMID 37750009›Full record

ArticleNMR in biomedicine2024

MRI-based quantification of whole-organ renal metabolic rate of oxygen.

Rajiv S Deshpande, Michael C Langham, Katalin Susztak, Felix W Wehrli

Erratum issuedAbstract read
In one paragraph

Article in NMR in biomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Recent Advances in MR Imaging-based Quantification of Brain Oxygen Metabolism.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Rajiv S DeshpandeLaboratory for Structural Physiologic and Functional Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Michael C LanghamLaboratory for Structural Physiologic and Functional Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Katalin SusztakDepartment of Medicine, Renal Electrolyte and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Felix W WehrliLaboratory for Structural Physiologic and Functional Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-3430-1840

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
High Spatial and Temporal Resolution MRI Mapping of Oxygen Consumption in HumansP41EB029460 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2021 to 2026
$7.6M
Training in Structural, Physiologic and Functional MRIT32EB020087 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, Chamith Sudesh Rajapakse · 2016 to 2026
$2.1M
MRI-Based Renal Oximetry in Early Diabetic Kidney DiseaseR21DK132556 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI WEHRLI, FELIX W · 2023 to 2024
$439k
Noninvasive Quantification of Renal Oxygen Utilization in Early Kidney DiseaseF30DK130510 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI DESHPANDE, RAJIV · 2021 to 2023
$77k
NCATS NIH HHS UL1 TR001878NIBIB NIH HHS P41 EB029460NIBIB NIH HHS T32 EB020087NIDDK NIH HHS F30 DK130510NIDDK NIH HHS R21 DK132556
6 · The paper itself

Abstract

During the early stages of diabetes, kidney oxygen utilization increases. The mismatch between oxygen demand and supply contributes to tissue hypoxia, a key driver of chronic kidney disease. Thus, whole-organ renal metabolic rate of oxygen (rMRO

Indexed as

Magnetic Resonance ImagingOxygenBiomarkersHumansKidneyReproducibility of ResultsBiomarkersOxygenkidneyMOTIVEoxygen metabolismrenal oxygenationT2-based oximetry

Identifiers

PMID37750009
PMCPMC10841084

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.