Evidence map›Paper›PMID 37749599›Full record

Observational studyArthritis research & therapy2023

Physical function and sex differences in radiographic axial spondyloarthritis: a cross-sectional analysis on Bath Ankylosing Spondylitis Functional Index.

Magnus Hallström, Eva Klingberg, Anna Deminger, Jeannette Beckman Rehnman, Mats Geijer, Helena Forsblad-d'Elia

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Arthritis research & therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Magnus HallströmDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 405 30, Gothenburg, Sweden. magnus.hallstrom@gu.se.ORCID http://orcid.org/0009-0009-4430-0228
Eva KlingbergDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 405 30, Gothenburg, Sweden.ORCID http://orcid.org/0000-0001-6858-6413
Anna DemingerDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 405 30, Gothenburg, Sweden.ORCID http://orcid.org/0000-0001-6423-1623
Jeannette Beckman RehnmanDepartment of Public Health and Clinical Medicine, Section of Medicine, Umeå University, Umeå, Sweden.ORCID http://orcid.org/0000-0001-6509-9644
Mats GeijerDepartment of Radiology, Institute of Clinical Sciences, University of Gothenburg, Gothenburg, Sweden.ORCID http://orcid.org/0000-0003-0529-7723
Helena Forsblad-d'EliaDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Box 480, 405 30, Gothenburg, Sweden.ORCID http://orcid.org/0000-0001-7871-5303
Sahlgrenska University Hospital · SELund University · SEUmeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysical function is an important determinant of health-related quality of life in radiographic axial spondyloarthritis patients (r-axSpA). To improve the basis of effective healthcare efforts, we aimed to investigate which demographic and disease-related factors that influence Bath Ankylosing Spondylitis Functional Index (BASFI) in r-axSpA patients overall and stratified by sex. Furthermore, we sought to explore differences between sexes regarding separate BASFI questions and also to explore which factors that may contribute to these differences.

methodsThis observational cross-sectional study included patients fulfilling the modified New York criteria for Ankylosing Spondylitis. Patients were assessed with 66/68 joint count and Bath Ankylosing Spondylitis Metrology Index (BASMI) measurements. Lateral X-rays were performed for Modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS). Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Ankylosing Spondylitis Disease Activity Score (ASDAS)-C-Reactive Protein (CRP), and BASFI were registered. Multivariable linear regression analyses were used to investigate which factors that associate with BASFI.

resultsA total of 353 r-axSpA patients were included, mean age 52.2 ± 12.7 years, 62.3% males. No significant sex difference was seen in BASFI scores (2.7 ± 2.0 in males vs 2.9 ± 2.1 in females). Age, body mass index, ASDAS-CRP, BASMI or mSASSS, fatigue, and tenderness were found to associate independently with BASFI in different models (R

conclusionsNo difference between male and female r-axSpA patients was seen in BASFI despite significant sex differences in BASMI, mSASSS, and CRP levels. Our results underline the impact of fatigue and tenderness on BASFI. The ability to climb stairs without a handrail was scored worse among females compared to males. Furthermore, the ability to look over the shoulder was worse in males than females and closely related to spinal mobility and structural spinal changes.

Indexed as

Axial SpondyloarthritisSpondylitis, AnkylosingAdultC-Reactive ProteinCross-Sectional StudiesFatigueFemaleHumansMaleMiddle AgedQuality of LifeSex CharacteristicsC-Reactive ProteinAnkylosing spondylitisCross-sectional studyFatigueFunctional performanceRadiographySexSpondyloarthritis

Identifiers

PMID37749599
PMCPMC10521572
OpenAlexW4387004183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.