ArticleScientific reports2023
Intradiscal cement leakage (ICL) increases the stress on adjacent vertebrae after kyphoplasty for osteoporotic vertebra compression fracture (OVCF): a finite-element study.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 9 citations in OpenAlex.
- Re-evaluating vertebral height restoration assessment in osteoporotic compression fractures: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Pooled it
- What Risk Factors Are Associated With Recurrent Osteoporotic Vertebral Compression Fractures After Percutaneous Vertebral Augmentation? A Meta-analysis.Clinical orthopaedics and related research · 2025Pooled it
- Incidence and prognostic factors of residual back pain in patients treated for osteoporotic vertebral compression fractures: a systematic review and meta-analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Pooled it
- Influence of Loading Modalities on Remodeling-Based Bone Formation in Severe OVCF Patients.International journal for numerical methods in biomedical engineering · 2026Article
- Association Between Adjacent Disc Vacuum Phenomenon and Adjacent Vertebral Fracture After Balloon Kyphoplasty for Osteoporotic Vertebral Fractures: A Retrospective Multicenter Study.Global spine journal · 2026Article
- AI-driven tissue discrimination sensing methods for robot-assisted spine surgery: a state-of-the-art review.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Analysis of risk factors and development of a predictive model for new vertebral fractures subsequent to percutaneous kyphoplasty in patients with single-segment osteoporotic vertebral compression fractures.BMC musculoskeletal disorders · 2026Article
- Stabilized C-reactive protein-albumin-lymphocyte (CALLY) index predicts adjacent fractures after kyphoplasty.BMC musculoskeletal disorders · 2026Article
- Biomechanical Effects of Cement Augmentation and Prophylactic Vertebroplasty on Adjacent Segment Stability in Multilevel Spinal Fusion: A Finite Element Analysis.Bioengineering (Basel, Switzerland) · 2025Article
- Article
- CORR Insights®: What Risk Factors Are Associated With Recurrent Osteoporotic Vertebral Compression Fractures After Percutaneous Vertebral Augmentation? A Meta-analysis.Clinical orthopaedics and related research · 2025Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to explore the biomechanical effects on adjacent vertebra of thoracolumbar Osteoporotic Vertebra Compression Fracture (OVCF) after Percutaneous Kyphoplasty (PKP) with intraoperative intradiscal cement leakage (ICL) by applying a Finite-Element Analysis. We collected pre- and post-operative computer tomography (CT) images of a 71-year-old female patient with single T12 OVCF, who underwent an intraoperative cement leakage into the T12-L1 disc. Three-dimensional finite element models of thoracolumbar spine (T10-L2) were built with the support of Materialise Interactive Medical Image Control System (MIMICS) and ABAQUS software. The stress on adjacent vertebrae and endplates under the uniform compressive pressure (0.3 MPa) and during different loading moments were analyzed. The three-dimensional finite element models reveal an asymmetrical distribution of von Mises stresses on the adjacent endplate unaffected by the surgical intervention. The maximum von Mises stress on adjacent vertebral bodies increased during different loading conditions, especially for lateral bending and rotation loading conditions, whereas the maximum von Mises stress on distal non-treated vertebrae decreased on anteflexion and backward extension loading conditions. Post-operative adjacent vertebra compression fractures after PKP with intraoperative intradiscal cement leakage (ICL) may be closely related to the biomechanical changes of adjacent vertebrae of thoracolumbar OVCF, and it may increase the risk of postoperative fracture.
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