Evidence map›Paper›PMID 37747636›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2024

Recommendations for the management of yttrium-90 radioembolization in the treatment of patients with colorectal cancer liver metastases: a multidisciplinary review.

Encarna González-Flores, Natalia Zambudio, Pedro Pardo-Moreno, Beatriz Gonzalez-Astorga, Jorge Roldán de la Rúa, Eva M Triviño-Ibáñez, Pablo Navarro, Nataly Espinoza-Cámac, Miguel Ángel Casado, Antonio Rodríguez-Fernández

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Encarna González-FloresMedical Oncology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.ORCID http://orcid.org/0000-0002-2077-5060
Natalia ZambudioSurgery Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.ORCID http://orcid.org/0000-0002-8477-9431
Pedro Pardo-MorenoRadiodiagnostic Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.ORCID http://orcid.org/0000-0003-0891-9006
Beatriz Gonzalez-AstorgaMedical Oncology Department, Hospital Universitario Clínico San Cecilio, Granada, Spain.ORCID http://orcid.org/0000-0002-9160-4680
Jorge Roldán de la RúaSurgery Department, Hospital Universitario Virgen de la Victoria, Málaga, Spain.ORCID http://orcid.org/0000-0003-3775-5274
Eva M Triviño-IbáñezNuclear Medicine Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.ORCID http://orcid.org/0000-0001-6604-6608
Pablo NavarroRadiodiagnostic Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Nataly Espinoza-CámacPharmacoeconomics and Outcomes Research Iberia (PORIB), Paseo Joaquín Rodrigo 4-I, Pozuelo de Alarcón, 28224, Madrid, Spain. nespinoza@porib.com.ORCID http://orcid.org/0000-0002-8116-6963
Miguel Ángel CasadoPharmacoeconomics and Outcomes Research Iberia (PORIB), Paseo Joaquín Rodrigo 4-I, Pozuelo de Alarcón, 28224, Madrid, Spain.ORCID http://orcid.org/0000-0002-8743-6653
Antonio Rodríguez-FernándezInstituto de Investigación Biosanitaria IBS, Granada, Spain.ORCID http://orcid.org/0000-0002-6068-3160
Hospital Universitario Virgen de las Nieves · ESInstituto de Investigación Biosanitaria de Granada · ESPharmacoeconomics and Health Outcomes Research Iberia (Spain) · ESHospital Clínico Universitario Virgen de la Victoria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeStrategies for the treatment of liver metastases from colon cancer (lmCRC) are constantly evolving. Radioembolization with yttrium 90 (Y-90 TARE) has made significant advancements in treating liver tumors and is now considered a potential option allowing for future resection. This study reviewed the scientific evidence and developed recommendations for using Y-90 TARE as a treatment strategy for patients with unresectable lmCRC.

methodsA multidisciplinary scientific committee, consisting of experts in medical oncology, hepatobiliary surgery, radiology, and nuclear medicine, all with extensive experience in treating patients with ImCRC with Y-90 TARE, led this project. The committee established the criteria for conducting a comprehensive literature review on Y-90 TARE in the treatment of lmCRC. The data extraction process involved addressing initial preliminary inquiries, which were consolidated into a final set of questions.

resultsThis review offers recommendations for treating patients with lmCRC using Y-90 TARE, addressing four areas covering ten common questions: 1) General issues (multidisciplinary tumor committee, indications for treatment, contraindications); 2) Previous process (predictive biomarkers for patient selection, preintervention tests, published evidence); 3) Procedure (standard procedure); and 4) Post-intervention follow-up (potential toxicity and its management, parameters for evaluation, quality of life).

conclusionsBased on the insights of the multidisciplinary committee, this document offers a comprehensive overview of the technical aspects involved in the management of Y-90 TARE. It synthesizes recommendations for applying Y-90 TARE across various phases of the treatment process.

Indexed as

Carcinoma, HepatocellularColorectal NeoplasmsLiver NeoplasmsHumansQuality of LifeYttrium RadioisotopesYttrium-90Yttrium RadioisotopesColonLiver metastasesRadioembolizationYttrium-90

Identifiers

PMID37747636
PMCPMC10981623
OpenAlexW4387002622

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.