ArticleEuropean journal of epidemiology2023
Moderate alcohol consumption, types of beverages and drinking pattern with cardiometabolic biomarkers in three cohorts of US men and women.
Article in European journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Lifestyle behaviours do not moderate the association between childhood maltreatment and comorbid depression and cardiometabolic disease in older adults: a meta-analysis.BMC medicine · 2025Pooled it
- Wine consumption, Mediterranean diet, and cardiovascular risk in two Spanish cohorts.European heart journal · 2026Trial
- Urinary tartaric acid as a biomarker of wine consumption and cardiovascular risk: the PREDIMED trial.European heart journal · 2025Trial
- Optimal measures of carbohydrate quality to lower the risk of type 2 diabetes: findings from 3 prospective cohort studies.The American journal of clinical nutrition · 2026Article
- Intake of Fiber From Different Food Sources and Type 2 Diabetes Risk: An Integrated Analysis of Epidemiological and Multiomic Data.Diabetes care · 2026Article
- Epidemiological and Multi-Omics Investigation of Phytosterol Intake and Type 2 Diabetes Risk.Research square · 2026Article
- The Unfinished Debate on Wine and Other Alcoholic Beverages: Conflicting Evidence, Public Health Messages and the Missing Trial.Nutrients · 2026Review
- Alcohol, the Mediterranean Diet and Cardiovascular Risks: Where is the New Evidence?European cardiology · 2026Review
- The dual role of APOE ε4 allele in cerebral small vessel disease: independent genetic effects and effect modification of traditional risk factors.Frontiers in neurology · 2026Article
- Lipid biomarkers of habitual alcohol intake and associations with pancreatic cancer risk.Journal of the National Cancer Institute · 2026Article
- The Mediterranean diet and cardiovascular disease.Cardiovascular research · 2025Review
- The Role of the Mediterranean Diet and Alcohol Consumption in Chronic Liver Disease Prevention: A Narrative Review.Medicina (Kaunas, Lithuania) · 2025Review
- Group-wise normalization in differential abundance analysis of microbiome samples.BMC bioinformatics · 2025Article
- Commentary: remaining questions on moderate alcohol drinking and cancer risk.Cancer causes & control : CCC · 2025Article
- Alcohol Intake, Drinking Pattern, and Risk of Type 2 Diabetes in Three Prospective Cohorts of U.S. Women and Men.Diabetes care · 2025Article
- Atherogenic Risk in Shift Versus Non-Shift Workers: Associations with Sociodemographic and Lifestyle Factors.Diseases (Basel, Switzerland) · 2025Article
- Microbiota-derived resveratrol metabolites: New biomarkers of red wine consumption are inversely associated with inflammation in a longitudinal study of a Mediterranean population.The journal of nutrition, health & aging · 2025Article
- Drinking pattern and time lag of alcohol consumption with colorectal cancer risk in US men and women.Journal of the National Cancer Institute · 2025Article
- Observational
- Adherence to the Mediterranean diet is associated with lower cancer-related fatigue: a cross-sectional analysis from NHANES 2017-2020.Frontiers in nutrition · 2025Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
Underlying mechanisms of the inverse relationship between moderate alcohol consumption and cardiometabolic disorders are unclear. Modification by types of alcoholic beverages consumed and drinking pattern remains understudied. We aimed to provide insight into the mechanisms by examining 14 insulinemic/glycemic, inflammatory and lipid markers. We used cross-sectional data from 15,436 women in the Nurses' Health Study, 19,318 women in the Nurses' Health Study II, and 6872 men in the Health Professionals Follow-up Study. Multivariable linear regression was used to estimate the percentage differences in biomarker concentrations according to alcohol intakes. The average alcohol intake in the combined cohort was 3.3 servings/week. We found a 1 serving/d increment in alcohol intake (14 g ethanol, 44 ml liquor or 355 ml beer or 118 ml wine per day) was associated with a 0.6% lower level of HbA1c, 1.7-3.6% lower proinflammatory markers and 4.2% higher adiponectin, as well as 7.1% higher HDL-cholesterol and 2.1% lower triglyceride with a significant linear trend. Wine, especially red wine, was associated with lower inflammation in particular. Beer had weaker favorable to null associations with blood lipids and adiponectin. Liquor was associated with higher C-peptide and interleukin-6, yet equally associated with lower HbA1c and higher HDL-cholesterol as other beverages. Drinking 3 days or more per week was related to a better biomarker profile than nonregular drinking independent of intake levels. Drinking appeared to have similar associations irrespective whether done with meals or not. Our data indicated moderate alcohol intake, especially if consumed from wine and done regularly, was associated with favorable profiles of insulinemic/glycemic and inflammatory markers and blood lipids.
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