Evidence map›Paper›PMID 37746790›Full record

ArticleJournal of the International Neuropsychological Society : JINS2024

Predicting neuropsychological late effects in pediatric brain tumor survivors using the Neurological Predictor Scale and the Pediatric Neuro-Oncology Rating of Treatment Intensity.

Alannah R Srsich, Mark D McCurdy, Peter M Fantozzi, Matthew C Hocking

Abstract read
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alannah R SrsichThe Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-8787-1487
Mark D McCurdyLifeStance Health, Northborough, MA, USA.
Peter M FantozziThe Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Matthew C HockingThe Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-1368-0856

Funding

A Prospective Study of Social Competence in Pediatric Brain Tumor SurvivorsK07CA178100 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI HOCKING, MATTHEW C. · 2013 to 2017
$639k
Neurocognitive and Family Functioning at End of Therapy in Pediatric Brain TumorR03CA162970 · NCI · CHILDREN'S HOSP OF PHILADELPHIA · PI HOCKING, MATTHEW C. · 2012 to 2013
$162k
NCI NIH HHS K07 CA178100NCI NIH HHS R03 CA162970
6 · The paper itself

Abstract

objectiveThe Neurological Predictor Scale (NPS) quantifies cumulative exposure to tumor- and treatment-related neurological risks. The Pediatric Neuro-Oncology Rating of Treatment Intensity (PNORTI) measures the intensity of different treatment modalities, but research is needed to establish whether it is associated with late effects. This study evaluated the predictive validity of the NPS and PNORTI for neuropsychological outcomes in pediatric brain tumor survivors.

methodA retrospective chart review was completed of pediatric brain tumor survivors (PBTS) (

resultsNPS scores ranged from 1 to 11 (

conclusionsThe findings suggest that the NPS has value in predicting IF and processing speed above-and-beyond demographic variables. The PNORTI was not associated with neuropsychological outcomes. Future research should consider establishing clinical cutoff scores for the NPS to help determine which survivors are most at risk for neuropsychological late effects and warrant additional assessment.

Indexed as

Brain NeoplasmsSurvivorsAdolescentChildCognitionDisease ProgressionHumansMemory, Short-TermNeuropsychological TestsRetrospective Studiesattentioncancercognitionintellectual functioningneurological complicationsneuropsychological assessment

Identifiers

PMID37746790
PMCPMC12012858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.