Evidence map›Paper›PMID 37746720›Full record

ReviewIntegrative cancer therapies

Moxibustion for the Treatment of Cancer and its Complications: Efficacies and Mechanisms.

Shanshan Lu, Bin Wang, Jiaqi Wang, Yi Guo, Shanshan Li, Suhong Zhao, Yuanzhen Yang, Yiting Feng, Zhifang Xu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Integrative cancer therapies. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Management of Fatigue in Adult Survivors of Cancer: ASCO-Society for Integrative Oncology Guideline Update.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Guideline
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  6. From traditional warming and tonifying to psychoneuroimmunology: theoretical reconstruction and clinical application of moxibustion for cancer-related fatigue.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
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  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shanshan LuTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, P. R. China.
Bin WangTianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin, P. R. China.
Jiaqi WangTianjin University of Traditional Chinese Medicine, Tianjin, P. R. China.
Yi GuoTianjin University of Traditional Chinese Medicine, Tianjin, P. R. China.
Shanshan LiTianjin University of Traditional Chinese Medicine, Tianjin, P. R. China.
Suhong ZhaoTianjin University of Traditional Chinese Medicine, Tianjin, P. R. China.
Yuanzhen YangTianjin University of Traditional Chinese Medicine, Tianjin, P. R. China.
Yiting FengTianjin University of Traditional Chinese Medicine, Tianjin, P. R. China.
Zhifang XuTianjin University of Traditional Chinese Medicine, Tianjin, P. R. China.ORCID 0000-0002-0576-163X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer treatment remains a significant challenge for the medical community, and improved therapies are necessary to treat cancer and its associated complications. Current anticancer therapies often have significant side effects, underscoring the need for new treatment options. Moxibustion is a representative external therapy used in traditional Chinese medicine. This review examines clinical studies demonstrating moxibustion's ability to improve the efficacy of radiotherapy and chemotherapy and control tumor progression. Moxibustion can prevent and treat various complications of cancer, including cancer-related or therapy-induced gastrointestinal symptoms, myelosuppression, fatigue, pain, and postoperative lymphedema. has also been shown to enhance the quality of life for cancer patients. However, very few studies have investigated the underlying mechanisms for these effects, a topic that requires systematic elucidation. Evidence has shown that moxibustion alone or combined with chemotherapy can improve survival and inhibit tumor growth in cancer-bearing animal models. The anticancer effect of moxibustion is associated with alleviating the tumor immunosuppressive and vascular microenvironments. Additionally, the therapeutic effects of moxibustion may originate from the heat and radiation produced during the combustion process on acupoints or lesions. This evidence provides a scientific basis for the clinical application of moxibustion in anticancer treatment and reducing the side effects of cancer therapies and helps promote the precise application of moxibustion in cancer treatment.

Indexed as

MoxibustionNeoplasmsFatigueHumansMedicine, Chinese TraditionalQuality of LifeTumor Microenvironmentcancerchemotherapycomplications of cancermoxibustionside-effect

Identifiers

PMID37746720
PMCPMC10521285

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.