ArticleMedComm2023
Single-cell RNA sequencing of retina revealed novel transcriptional landscape in high myopia and underlying cell-type-specific mechanisms.
Article in MedComm, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The trial behind it
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Who cites it
21 citing papers in PubMed.
- Multifunctional Catechol-Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries.Advanced healthcare materials · 2026Article
- Single-cell RNA sequencing reveals lipid metabolism disorders in the retina in spontaneous high myopia.Biology direct · 2026Article
- Single-Cell Sequencing Analysis Reveals Dysregulated Energy Metabolism and Altered Synaptic Connectivity in the Mouse Retina Following Dark Rearing.Investigative ophthalmology & visual science · 2026Article
- The Effect of Optic Nerve Crush on Lens-Induced Myopia in Mice.Ophthalmology science · 2026Article
- Relationship between choroidal thickness changes and macrophage polarization in high myopia.Frontiers in medicine · 2026Review
- Role of light in eye growth and light as a therapy for myopia control.Frontiers in ophthalmology · 2026Review
- Cellular Biological Basis and Novel Breakthroughs in the Pathogenesis of Myopia - A Narrative Review.International journal of general medicine · 2026Review
- Single-Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Amine-responsive Rhodopsin-like GPCRs in ocular pathology: mechanistic associations, candidate biomarkers, and therapeutic potential.Frontiers in physiology · 2026Review
- Myo-inflam: a mini review on inflammatory pathways driving scleral remodeling and axial elongation.Frontiers in immunology · 2026Review
- Single-cell profiling reveals a shared proinflammatory macrophage signature across multiple organs in myopia.Cell discovery · 2025Article
- An innovative diagnostic method for myopia using blood-based biomemristor.Materials today. Bio · 2025Article
- Integrating Single-Cell and Spatial Transcriptomics Reveals NK Cell Subpopulations Associated With Immunotherapy for Melanoma.Smart medicine · 2025Article
- Inflammation and Immune Pathways in Myopia: An Overview on Pathomechanisms and Treatment Prospects.Clinical reviews in allergy & immunology · 2025Review
- The Advance of Single-Cell RNA Sequencing Applications in Ocular Physiology and Disease Research.Biomolecules · 2025Review
- Myopia development: multifactorial interplay, molecular mechanisms and possible strategies.Frontiers in medicine · 2025Review
- Exploring genotype-phenotype correlations in pathological myopia: a case report.Frontiers in medicine · 2025Article
- Early Alterations in Inner-Retina Neural and Glial Saturated Responses in Lens-Induced Myopia.Translational vision science & technology · 2024Article
- Multi-omics in exploring the pathophysiology of diabetic retinopathy.Frontiers in cell and developmental biology · 2024Review
- Retinal glia in myopia: current understanding and future directions.Frontiers in cell and developmental biology · 2024Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High myopia is a leading cause of blindness worldwide with increasing prevalence. Retina percepts visual information and triggers myopia development, but the underlying etiology is not fully understood because of cellular heterogeneity. In this study, single-cell RNA sequencing analysis was performed on retinas of mouse highly myopic and control eyes to dissect the involvement of each cell type during high myopia progression. For highly myopic photoreceptors,
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Registered trials
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