Evidence map›Paper›PMID 37746214›Full record

ArticleFrontiers in fungal biology2022

Antioxidant activity of mycelia methanolic extracts of endophytic fungi BvFV and BvFIX isolated from leaves of

Daniela Gurgel de Freitas Pires, Laíza Magalhães de Araújo, Pedro Góes Mesquita, Francisco de Assis Rocha Neves, Maria de Fátima Borin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in fungal biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. The use of natural extracts with photoprotective activity: a 2015-2023 patent prospection.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Daniela Gurgel de Freitas PiresLaboratory of Molecular Pharmacology, Department of Pharmacy, Health Sciences Faculty, University of Brasilia, Brasilia, Brazil.
Laíza Magalhães de AraújoLaboratory of Molecular Pharmacology, Department of Pharmacy, Health Sciences Faculty, University of Brasilia, Brasilia, Brazil.
Pedro Góes MesquitaLaboratory of Molecular Pharmacology, Department of Pharmacy, Health Sciences Faculty, University of Brasilia, Brasilia, Brazil.
Francisco de Assis Rocha NevesLaboratory of Molecular Pharmacology, Department of Pharmacy, Health Sciences Faculty, University of Brasilia, Brasilia, Brazil.
Maria de Fátima BorinLaboratory of Molecular Pharmacology, Department of Pharmacy, Health Sciences Faculty, University of Brasilia, Brasilia, Brazil.
Universidade de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endophytes are considered an essential source of natural products. Skin is the body's largest organ; its primary function is the protection of other organs, and aging is one of the most relevant problems associated with this organ. UV radiation generates reactive oxygen species (ROS), which lead to skin degeneration and consequent aging. The main endogenous antioxidants that neutralize ROS are enzymatic antioxidants such as superoxide dismutase (SOD), catalase, glutathione peroxidase, and glutathione reductase, and non-enzymatic antioxidants, such as glutathione and α-tocopherol. Nuclear receptors are involved in molecular mechanisms that control the aging process, especially peroxisome proliferator-activated receptors (PPAR), which regulate the function and expression of genes that modulate the balance between matrix metalloproteinases (MMP) activity and the expression of collagen. Some natural compounds, such as polyphenols, can activate PPAR and reduce the activation of MMP and collagen degradation. In this work, the antioxidant activity of the mycelia methanolic extracts of two endophytic fungi isolated from leaves of

Indexed as

antioxidantBauhinia variegataendophytic fungusfibroblastsPPARskin aging

Identifiers

PMID37746214
PMCPMC10512253
OpenAlexW4311111735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.