Evidence map›Paper›PMID 37746158›Full record

ArticleHemaSphere2023

Thiotepa-busulfan-fludarabine Compared to Treosulfan-based Conditioning for Haploidentical Transplant With Posttransplant Cyclophosphamide in Patients With Acute Myeloid Leukemia in Remission: A Study From the Acute Leukemia Working Party of the EBMT.

Francesco Saraceni, Myriam Labopin, Anna M Raiola, Didier Blaise, Péter Reményi, Federica Sorà, Jiri Pavlu, Stefania Bramanti, Alessandro Busca, Ana Berceanu and 13 more

Open access · goldAbstract read
In one paragraph

Article in HemaSphere, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

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  4. Total body irradiation-based conditioning in allogeneic transplantation in patients with hematological malignancies: impact in outcomes by stem-cell source.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 14 institutions in 8 countries.

Francesco SaraceniEmatologia, Trapianto e Terapia Cellulare, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy.ORCID https://orcid.org/0000-0001-6500-9514
Myriam LabopinSorbonneUniversité, INSERM UMR-S 938, CRSA, EBMT Statistical Unit, Paris, France.
Anna M RaiolaEmatoloia e Terapia Cellulare, IRCCS Ospedale Policlinico San Martino Genova, Italy.
Didier BlaiseProgramme de Transplantation and TherapieCellulaire, Centre de RechercheenCancérologie de Marseille, Institut Paoli Calmettes, Marseille, France.
Péter ReményiDepartment of Hematology and Stem Cell Transplant, Budapest, Hungary.
Federica SoràUniversitaCattolica S. Cuore, Istituto di Ematologia, Rome, Italy.
Jiri PavluDepartment of Hematology, Imperial College, Hammersmith Hospital, London, United Kingdom.
Stefania BramantiDepartment of Oncology and Hematology, IstitutoClinicoHumanitas, Transplantation Unit, Milano, Italy.
Alessandro BuscaS.S.C.V.D Trapianto di Cellule Staminali, A.O.U Cittadella Salute e dellaScienza di Torino, Italy.
Ana BerceanuHopital Jean Minjoz, Service d`Hématologie, Besançon, France.
Giorgia BattipagliaDivision of Hematology, Federico II` Medical School, University of Napoli, Italy.
Giuseppe VisaniHematology and Transplant Center, AORMN Hospital, Pesaro, Italy.
Gerard SocièDepartment of Hematology, Hopital St. Louis, BMT, Paris, France.
Gesine BugGoethe-Universitaet, MedizinischeKlinik II, Hämatologie, MedizinischeOnkologie, Frankfurt_Main, Germany.
Caterina MicòHematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, Italy.
Giorgio La NasaCentro TrapiantiUnico Di CSE Adulti e Pediatrico A. O Brotzu, Cagliari, Italy.
Maurizio MussoDepartment of Oncologico, Ospedale La Maddalena, Palermo, Italy.
Attilio OlivieriEmatologia, Trapianto e Terapia Cellulare, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy.
Alexandros SpyridonidisBone Marrow Transplantation Unit and Institute of Cell Therapy, University of Patras, Greece.
Bipin SavaniLong Term Transplant Clinic, Vanderbilt University Medical Center, Nashville, TN, USA.
Fabio CiceriOspedale San Raffaele s.r.l., Hematology and BMT, Milano, Italy.
Arnon NaglerHematology Division, ChaimShebaMedical Center, Tel-Hashomer, Israel.
Mohamad MohtySorbonneUniversité, INSERM UMR-S 938, CRSA, Service d'hématologie et thérapie cellulaire, AP-HP, Hôpital Saint-Antoine, Paris, France.
Azienda Ospedaliero Universitaria Ospedali Riuniti · ITHammersmith Hospital · GBInserm · FRCentre de Recherche en Cancérologie de Marseille · FRCTO Hospital · ITGoethe University Frankfurt · DEGruppo Italiano per il Trapianto di Midollo Osseo · ITHungarian National Blood Transfusion Service · HUIRCCS Ospedale San Raffaele · ITIstituto di Ematologia di Bologna · ITOspedale Papa Giovanni XXIII · ITOspedale Policlinico San Martino · ITSheba Medical Center · ILUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We conducted a registry analysis including adult acute myeloid leukemia (AML) patients in remission who had received thiotepa, busulfan, and fludarabine (TBF) or treosulfan-based (Treo) conditioning for haplo-hematopoietic stem cell transplant (HSCT) with posttransplant cyclophosphamide (PTCy) between 2010 and 2020. A total of 1123 patients met the inclusion criteria (968 received TBF and 155 received Treo). A 1:1 matched-pair analysis was performed on 142 TBF and 142 Treo patients. In the Treo group, 68% of patients received treosulfan at a dose ≥36 g/m

Identifiers

PMID37746158
PMCPMC10513143
OpenAlexW4386882751

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.