ReviewFrontiers in fungal biology2023
Tridepsides as potential bioactives: a review on their chemistry and the global distribution of their lichenic and non-lichenic natural sources.
Review in Frontiers in fungal biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Lichen-Derived Bioactive Compounds in Diabetes and Cardiovascular Risk: Experimental Evidence, Mechanisms, and Translational Challenges.Biomedicines · 2026Review
- Deciphering the biosynthetic pathways of lichen acids.The New phytologist · 2026Article
- A Comprehensive Review on Chemical Structures and Bioactivities ofJournal of fungi (Basel, Switzerland) · 2025Review
- Gyrophoric Acid, a Secondary Metabolite of Lichens, Exhibits Antidepressant and Anxiolytic Activity In Vivo in Wistar Rats.International journal of molecular sciences · 2024Article
- A Review of Laboratory Requirements to Culture Lichen Mycobiont Species.Journal of fungi (Basel, Switzerland) · 2024Review
- It Is Not All about Alkaloids-Overlooked Secondary Constituents in Roots and Rhizomes ofPlants (Basel, Switzerland) · 2024Article
- Exploring the Diversity and Systematics ofJournal of fungi (Basel, Switzerland) · 2023Article
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Authors and funding
4 authors.
Funding
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Abstract
Tridepsides, as fully oxidized polyketides, have been known to exist in lichens for more than a century. Recent studies have showed that these possible defensive lichenochemicals possess various biological activities. Also, a candidate biosynthetic gene cluster was recently reported for gyrophoric acid (GA), an important tridepside. The present study focused on biosynthesis, natural sources, biological activities, and bioanalytical methods of tridepside molecules. Our survey shows that, so far, lichenic tridepsides have been reported from 37 families, 111 genera, and 526 species of lichen. Because many of their species contain tridepsides, the families Parmeliaceae, Lobariaceae, and Peltigeraceae can be considered critical lichenic sources of tridepsides. Furthermore, several species of
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