ArticleFrontiers in medicine2023
Elevated CK-MB levels are associated with adverse clinical outcomes in acute pancreatitis: a propensity score-matched study.
Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- A Hyperbranched Rolling Circle Amplification Assay Using Aptamer-Hemin/G-Quadruplex Recognition for the Detection of Creatine Kinase-MB.ACS measurement science au · 2026Article
- An interpretable XGboost algorithm for predicting 30-day mortality in acute pancreatitis using routine biomarkers.BMC medical research methodology · 2026Article
- Article
- Construction of a Mortality Prediction Model for Cardiac Arrest Patients Using Lactate Clearance Rate and Albumin-Corrected Anion Gap.Emergency medicine international · 2026Article
- Creatine kinase-MB elevation in patients with acute aortic dissection predict worse in-hospital outcomes.International journal of cardiology. Heart & vasculature · 2025Article
- Cardiac complications in acute pancreatitis: an under-diagnosed clinical concern.World journal of emergency medicine · 2025Article
- Development and external validation of a nomogram for the early prediction of acute kidney injury in septic patients: a multicenter retrospective clinical study.Renal failure · 2024Article
- Establishment and Validation of an Early Predictive Model for Severe Acute Pancreatitis.Journal of inflammation research · 2024Article
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11 authors.
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Abstract
Aim: Cardiac injury, reflected by the measured concentrations of chemicals released from injured cardiac muscle, is common in acute pancreatitis (AP). However, there is no adequate evidence assessing the impact of cardiac injury on AP-related outcomes. Creatine kinase-myocardial band (CK-MB) mainly exists in the myocardium. Therefore, we sought to evaluate the relationship between the increase in CK-MB and the adverse clinical outcomes of AP. Methods: This propensity score-matched study analyzed AP patients admitted to the Department of Gastroenterology in the First Affiliated Hospital of Nanchang University from June 2017 to July 2022. Propensity score matching and multivariate logistic regression analysis were used to explore the relationship between CK-MB elevation and AP outcome variables. Results: A total of 5,944 patients were screened for eligibility, of whom 4,802 were ultimately enrolled. Overall, 896 (18.66%) of AP patients had elevated (>24 U/ml) CK-MB levels, and 895 (99.89%) were paired with controls using propensity score matching. The propensity score-matched cohort analysis demonstrated that mortality (OR, 5.87; 95% CI, 3.89-8.84; Conclusion: CK-MB elevation was significantly related to adverse outcomes in AP patients, which makes it a potentially useful laboratory parameter for predicting adverse clinical outcomes of AP.
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