Evidence map›Paper›PMID 37745839›Full record

ArticleTherapeutic advances in medical oncology2023

Role of immunotherapy in chondrosarcoma: A case report and review of the literature.

Adam J Cohen-Nowak, Danielle B Dressler, Adam Rock, Katherine Mojica, Doni Woo, Lee M Zuckerman, Warren Chow, Mark Agulnik

Abstract readCase Reports
In one paragraph

Article in Therapeutic advances in medical oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Adam J Cohen-NowakMcGaw Medical Center of Northwestern University, Chicago, IL, USA.ORCID https://orcid.org/0000-0001-6784-7159
Danielle B DresslerMcGaw Medical Center of Northwestern University, Chicago, IL, USA.
Adam RockCity of Hope Comprehensive Cancer Center, Duarte, CA, USA.
Katherine MojicaCity of Hope Comprehensive Cancer Center, Duarte, CA, USA.
Doni WooCity of Hope Comprehensive Cancer Center, Duarte, CA, USA.
Lee M ZuckermanCity of Hope Comprehensive Cancer Center, Duarte, CA, USA.ORCID https://orcid.org/0000-0001-7762-2906
Warren ChowUniversity of California, Irvine, Irvine, CA, USA.ORCID https://orcid.org/0000-0003-0889-5841
Mark AgulnikDepartment of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chondrosarcomas (CSs) consist of a heterogenous group of primary bone cancers arising from malignant cells which produce cartilaginous matrix. As the second most common primary bone cancer, CS are often resistant to systemic chemotherapy due to poor vascularization, slow proliferation, and expression of multidrug-resistant pumps. Immune checkpoint inhibitors have transformed the field of oncology and are now designated as frontline therapy for many solid tumor cancers. Several studies have demonstrated increased expression of programed cell death 1 (PD-1) and PD-L1 in CS tissue

Indexed as

anti-PD-1checkpoint inhibitorchondrosarcomadrug resistanceimmunotherapytumor microenvironment

Identifiers

PMID37745839
PMCPMC10515522

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.