Evidence map›Paper›PMID 37745833›Full record

ArticleNature electronics2023

Location-aware ingestible microdevices for wireless monitoring of gastrointestinal dynamics.

Saransh Sharma, Khalil B Ramadi, Nikhil H Poole, Shriya S Srinivasan, Keiko Ishida, Johannes Kuosmanen, Josh Jenkins, Fatemeh Aghlmand, Margaret B Swift, Mikhail G Shapiro and 2 more

Abstract read
In one paragraph

Article in Nature electronics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. AI-Enhanced Vibrational Capsule for Minimally Invasive Detection of Abnormal Bowel Tissue.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Acoustic percolation switches enable targeted drug delivery controlled by diagnostic ultrasound.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. A Fully Edible Transistor Based on a Toothpaste Pigment.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Saransh SharmaDepartment of Electrical Engineering, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-5052-4932
Khalil B RamadiDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Nikhil H PooleDepartment of Electrical Engineering, California Institute of Technology, Pasadena, CA, USA.
Shriya S SrinivasanDivision of Gastroenterology, Hepatology and Endoscopy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Keiko IshidaDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Johannes KuosmanenDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.
Josh JenkinsDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID 0000-0001-7698-9888
Fatemeh AghlmandDepartment of Electrical Engineering, California Institute of Technology, Pasadena, CA, USA.
Margaret B SwiftDepartment of Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.
Mikhail G ShapiroDepartment of Chemical Engineering, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-0291-4215
Giovanni TraversoDepartment of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID 0000-0001-7851-4077
Azita EmamiDepartment of Electrical Engineering, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-6945-9958

Funding

CONTROLLED RELEASE OF MACROMOLECULESR01EB000244 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI LANGER, ROBERT SAMUEL, TRAVERSO, CARLO GIOVANNI · 2002 to 2021
$6.1M
Simultaneous gastric and brain electrical interfacing for development of endoscopic gastric stimulation treatments for gastroparesisF32DK122762 · NIDDK · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI RAMADI, KHALIL · 2020 to 2020
$32k
NIBIB NIH HHS R01 EB000244NIDDK NIH HHS F32 DK122762
6 · The paper itself

Abstract

Localization and tracking of ingestible microdevices in the gastrointestinal (GI) tract is valuable for the diagnosis and treatment of GI disorders. Such systems require a large field-of-view of tracking, high spatiotemporal resolution, wirelessly operated microdevices and a non-obstructive field generator that is safe to use in practical settings. However, the capabilities of current systems remain limited. Here, we report three dimensional (3D) localization and tracking of wireless ingestible microdevices in the GI tract of large animals in real time and with millimetre-scale resolution. This is achieved by generating 3D magnetic field gradients in the GI field-of-view using high-efficiency planar electromagnetic coils that encode each spatial point with a distinct magnetic field magnitude. The field magnitude is measured and transmitted by the miniaturized, low-power and wireless microdevices to decode their location as they travel through the GI tract. This system could be useful for quantitative assessment of the GI transit-time, precision targeting of therapeutic interventions and minimally invasive procedures.

Identifiers

PMID37745833
PMCPMC10516531

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.