Evidence map›Paper›PMID 37745671›Full record

ArticleFrontiers in neurology2023

Impact of e-ASPECTS software on the performance of physicians compared to a consensus ground truth: a multi-reader, multi-case study.

Hassan Kobeissi, David F Kallmes, John Benson, Alex Nagelschneider, Ajay Madhavan, Steven A Messina, Kara Schwartz, Norbert Campeau, Carrie M Carr, Deena M Nasr and 14 more

Abstract read
In one paragraph

Article in Frontiers in neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Hassan KobeissiDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.
David F KallmesDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.
John BensonDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.
Alex NagelschneiderDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.
Ajay MadhavanDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.
Steven A MessinaDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.
Kara SchwartzDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.
Norbert CampeauDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.
Carrie M CarrDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.
Deena M NasrDepartment of Neurology, Mayo Clinic, Rochester, MN, United States.
Sherri BraksickDepartment of Neurology, Mayo Clinic, Rochester, MN, United States.
Eugene L ScharfDepartment of Neurology, Mayo Clinic, Rochester, MN, United States.
James KlaasDepartment of Neurology, Mayo Clinic, Rochester, MN, United States.
Zoe Victoria Joan WoodheadBrainomix Limited, Oxford, United Kingdom.
George HarstonBrainomix Limited, Oxford, United Kingdom.
James BriggsBrainomix Limited, Oxford, United Kingdom.
Olivier JolyBrainomix Limited, Oxford, United Kingdom.
Stephen GerryCentre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom.
Anna L KuhnDivision of Neurointerventional Radiology, Department of Radiology, UMass Medical Center, Worcester, MA, United States.
Angelos A KostasHuntington Hospital and Hill Medical Imaging, Pasadena, CA, United States.
Kambiz NaelDepartment of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles (UCLA), Los Angeles, CA, United States.
Mohamad AbdalKaderDepartment of Radiology, Boston Medical Center, Boston, MA, United States.
Ramanathan KadirvelDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.
Waleed BrinjikjiDepartment of Radiology, Mayo Clinic, Rochester, MN, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Alberta Stroke Program Early CT Score Methods: The study used a multi-reader, multi-case design. A total of 10 US board-certified physicians (neurologists and neuroradiologists) scored 54 NCCT brain scans of patients with AIS affecting the MCA territory. Each reader scored each scan on two occasions: once with and once without reference to the e-ASPECTS software, in random order. Agreement with a reference standard (expert consensus read with reference to follow-up imaging) was evaluated with and without software support. Results: A comparison of the area under the curve (AUC) for each reader showed a significant improvement from 0.81 to 0.83 ( Conclusion: Decision support with the e-ASPECTS software significantly improves the accuracy of ASPECTS scoring, even by expert US neurologists and neuroradiologists.

Indexed as

ASPECTSimagingneuroradiologystrokethrombectomy

Identifiers

PMID37745671
PMCPMC10513025

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.