Evidence map›Paper›PMID 37745590›Full record

ArticlebioRxiv : the preprint server for biology2023

Concurrent administration of COVID-19 and influenza vaccines enhances Spike-specific antibody responses.

Susanna E Barouch, Taras M Chicz, Ross Blanc, Domenic R Barbati, Lily J Parker, Xin Tong, Ryan P McNamara

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Susanna E BarouchRagon Institute of MGH, MIT, and Harvard.
Taras M ChiczRagon Institute of MGH, MIT, and Harvard.
Ross BlancRagon Institute of MGH, MIT, and Harvard.
Domenic R BarbatiRagon Institute of MGH, MIT, and Harvard.
Lily J ParkerRagon Institute of MGH, MIT, and Harvard.
Xin TongRagon Institute of MGH, MIT, and Harvard.
Ryan P McNamaraRagon Institute of MGH, MIT, and Harvard.
Ragon Institute of MGH, MIT and Harvard · US

Funding

COVID Supplement - COMPONENT A OF THE COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTERS (CIVICS) PROGRAM TO DESIGN AND EVALUATE INNOVATIVE INFLUENZA VACCINE APPROACHES,75N93019C00052 · NIAID · UNIVERSITY OF GEORGIA · PI ROSS, TED · 2019 to 2025
$74.6M
Technology and Computational CoreP01AI165072 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI SAPHIRE, ERICA OLLMANN · 2021 to 2023
$19.6M
The Development and Evaluation of Pan-Coronavirus VaccinesP01AI168347 · NIAID · WASHINGTON UNIVERSITY · PI Michael S Diamond, Sean PJ Whelan · 2022 to 2026
$15.9M
Immunologic Signatures of SARS-CoV-2 Vaccination and DiseaseU01CA260476 · NCI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BAROUCH, DAN H. · 2020 to 2024
$3.7M
NCI NIH HHS U01 CA260476NIAID NIH HHS 75N93019C00052NIAID NIH HHS P01 AI165072NIAID NIH HHS P01 AI168347Wellcome Trust
6 · The paper itself

Abstract

The bivalent COVID-19 mRNA boosters became available in fall 2022 and were recommended alongside the seasonal influenza vaccine. However, the immunogenicity of concurrent versus separate administration of these vaccines remains unclear. Here, we analyzed antibody responses in healthcare workers who received the bivalent COVID-19 booster and the influenza vaccine on the same day or different days. IgG1 responses to SARS-CoV-2 Spike were higher at peak immunogenicity and 6 months following concurrent administration compared with separate administration of the COVID-19 and influenza vaccines. These data suggest that concurrent administration of these vaccines may yield higher and more durable SARS-CoV-2 antibody responses.

Indexed as

bivalentCOVID-19heterologous vaccineinfluenzaOmicronSARS-CoV-2vaccineXBB.1.5

Identifiers

PMID37745590
PMCPMC10515870
OpenAlexW4386647637

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.